Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 2/20 | 0.48 |
| ▸ | FSCN1 | Q16658 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 3/20 | 0.41 |
| ▸ | TP53 | P04637 | 4/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | TSPO | P30536 | 1/20 | 0.39 |
| ▸ | THRB | P10828 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11184627 | 0.84 | POLB (0.48) | POLBKDM4ESMN1; SMN2ALDH1A1MAPT | |
| SCHEMBL13043265 | 0.84 | FSCN1 (0.50) | FSCN1KDM4ESMN1; SMN2ALDH1A1RAB9A | |
| SCHEMBL10944146 | 0.82 | POLB (0.47) | POLBKDM4ESMN1; SMN2ALDH1A1MAPT | |
| SCHEMBL20708217 | 0.81 | FSCN1 (0.56) | FSCN1KDM4ESMN1; SMN2ALDH1A1RAB9A | |
| SCHEMBL4910933 | 0.81 | FSCN1 (0.43) | POLBFSCN1SMN1; SMN2ALDH1A1RAB9A | |
| SCHEMBL14098357 | 0.81 | FSCN1 (0.43) | POLBFSCN1KDM4ESMN1; SMN2ALDH1A1 | |
| SCHEMBL20264504 | 0.80 | POLB (0.43) | POLBKDM4ESMN1; SMN2MAPTTP53 | |
| SCHEMBL20264395 | 0.79 | POLB (0.45) | POLBKDM4EMAPTTP53GAA | |
| SCHEMBL29940563 | 0.79 | POLB (0.45) | POLBKDM4EMAPTTP53GAA | |
| SCHEMBL28678688 | 0.78 | ALDH1A1 (0.53) | POLBFSCN1SMN1; SMN2ALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023154282-A1 | COMPOUNDS HAVING A T-STRUCTURE FORMED BY AT LEAST FOUR CYCLES FOR USE IN THE TREATMENT OF CANCER AND OTHER INDICATIONS | THERAS, INC. (US) | 2023-08-17 | — | — | WO | disclosed |