Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DGAT1 | O75907 | 2/20 | 0.38 |
| ▸ | PIK3CA | P42336 | 4/20 | 0.33 |
| ▸ | HDAC6 | Q9UBN7 | 7/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
| ▸ | EGFR | P00533 | 1/20 | 0.31 |
| ▸ | IGF1R | P08069 | 1/20 | 0.31 |
| ▸ | SRC | P12931 | 1/20 | 0.31 |
| ▸ | FLT4 | P35916 | 1/20 | 0.31 |
| ▸ | KDR | P35968 | 1/20 | 0.31 |
| ▸ | FLT3 | P36888 | 1/20 | 0.31 |
| ▸ | EPHB4 | P54760 | 1/20 | 0.31 |
| ▸ | TEK | Q02763 | 1/20 | 0.31 |
| ▸ | KLKB1 | P03952 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
| ▸ | NPC1 | O15118 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21552930 | 0.93 | PIK3CA (0.39) | DGAT1PIK3CAHDAC6ALDH1A1 | |
| SCHEMBL21552897 | 0.93 | DGAT1 (0.40) | DGAT1EGFRIGF1RSRCFLT4 | |
| SCHEMBL21552983 | 0.92 | DGAT1 (0.39) | DGAT1HDAC6ALDH1A1EGFRIGF1R | |
| SCHEMBL21553048 | 0.86 | DGAT1 (0.41) | DGAT1HDAC6KLKB1NPC1 | |
| SCHEMBL21552892 | 0.84 | DGAT1 (0.38) | DGAT1KLKB1 | |
| SCHEMBL21552956 | 0.82 | ABL1 (0.40) | DGAT1PIK3CAALDH1A1MAPK1KLKB1 | |
| SCHEMBL21553006 | 0.82 | DGAT1 (0.36) | DGAT1KLKB1NPC1 | |
| SCHEMBL21552888 | 0.81 | DGAT1 (0.37) | DGAT1KLKB1 | |
| SCHEMBL26031604 | 0.81 | DGAT1 (0.35) | DGAT1HDAC6ALDH1A1KLKB1NPC1 | |
| SCHEMBL21553030 | 0.80 | DGAT1 (0.39) | DGAT1PIK3CAKLKB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230250090-A1 | KDM1A INHIBITORS FOR THE TREATMENT OF DISEASE | IMAGO BIOSCIENCES INC (US) | 2023-08-10 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230250090-A1 | KDM1A INHIBITORS FOR THE TREATMENT OF DISEASE | KDM1B, KDM1A, KDM2A | DGAT1 2741/4885PIK3CA 3931/4885HDAC6 2063/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.