Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.44 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.42 |
| ▸ | ZDHHC7 | Q9NXF8 | 1/20 | 0.41 |
| ▸ | ACHE | P22303 | 4/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | MTNR1A | P48039 | 2/20 | 0.38 |
| ▸ | MTNR1B | P49286 | 2/20 | 0.38 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.38 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | BLM | P54132 | 1/20 | 0.38 |
| ▸ | ATM | Q13315 | 1/20 | 0.38 |
| ▸ | PAOX | Q6QHF9 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5088794 | 0.81 | ZDHHC7 (0.59) | TSHRADRA1AALDH1A1KDM4EMAPK1 | |
| SCHEMBL23922522 | 0.80 | TSHR (0.60) | TSHRADRA1AALDH1A1KDM4EMAPK1 | |
| SCHEMBL22431364 | 0.80 | PAOX (0.61) | TSHRADRA1AALDH1A1KDM4EMAPK1 | |
| SCHEMBL15241525 | 0.78 | ZDHHC7 (0.54) | TSHRADRA1AALDH1A1KDM4EMAPK1 | |
| SCHEMBL19192288 | 0.77 | KDM4E (0.65) | TSHRADRA1AALDH1A1KDM4EMAPK1 | |
| SCHEMBL16260817 | 0.75 | TSHR (0.54) | TSHRADRA1AALDH1A1KDM4EMAPK1 | |
| SCHEMBL18734790 | 0.74 | TSHR (0.62) | TSHRADRA1AALDH1A1KDM4EMAPK1 | |
| SCHEMBL16353072 | 0.74 | CYP2C19 (0.60) | TSHRADRA1AKDM4EACHECYP2C19 | |
| SCHEMBL8763339 | 0.74 | KDM4E (0.61) | TSHRADRA1AALDH1A1KDM4EMAPK1 | |
| SCHEMBL17164980 | 0.74 | ADRA1A (0.55) | TSHRADRA1AALDH1A1KDM4EMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11739122-B2 | Glycopeptide antibiotic compounds, methods for producing the same, and uses thereof | ACADEMIA SINICA (TW) | 2023-08-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11739122-B2 | Glycopeptide antibiotic compounds, methods for producing the same, and uses thereof | NGLY1, NRDC, MGAT3 | TSHR 291/4885ADRA1A 3767/4885ALDH1A1 3782/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.