Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 5/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | TK2 | O00142 | 8/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 2/20 | 0.33 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | TK1 | P04183 | 1/20 | 0.32 |
| ▸ | THRB | P10828 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.31 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24205081 | 0.91 | TSHR (0.45) | TSHRALDH1A1CYP3A4HPGDTK2 | |
| SCHEMBL26035287 | 0.89 | TSHR (0.44) | TSHRALDH1A1CYP3A4HPGDTK2 | |
| SCHEMBL24205063 | 0.86 | TSHR (0.45) | TSHRALDH1A1CYP3A4HPGDCYP2C9 | |
| SCHEMBL24205256 | 0.83 | TSHR (0.43) | TSHRALDH1A1TK2CYP2C9KMT2A | |
| SCHEMBL24205267 | 0.81 | ALDH1A1 (0.40) | TSHRALDH1A1CYP3A4HPGDTK2 | |
| SCHEMBL26035357 | 0.81 | ALDH1A1 (0.40) | TSHRALDH1A1CYP3A4HPGDTK2 | |
| SCHEMBL26035285 | 0.81 | TK2 (0.53) | TSHRALDH1A1CYP3A4TK2CYP2C9 | |
| SCHEMBL26034606 | 0.81 | TK2 (0.53) | TSHRALDH1A1CYP3A4TK2CYP2C9 | |
| SCHEMBL26035304 | 0.80 | TSHR (0.44) | TSHRALDH1A1CYP3A4HPGDCYP2C9 | |
| SCHEMBL24205055 | 0.78 | TSHR (0.47) | TSHRALDH1A1CYP3A4HPGDTP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230273455-A1 | OPTICALLY ACTIVE DEVICES | JOHNSON & JOHNSON SURGICAL VISION INC (US) | 2023-08-31 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230273455-A1 | OPTICALLY ACTIVE DEVICES | PDE6C, PDE6A, PDE6D | TSHR 4592/4885ALDH1A1 311/4885CYP3A4 2513/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.