Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGFR | P00533 | 9/20 | 0.54 |
| ▸ | CDK1 | P06493 | 5/20 | 0.54 |
| ▸ | SRC | P12931 | 1/20 | 0.54 |
| ▸ | MAPT | P10636 | 4/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.51 |
| ▸ | TP53 | P04637 | 3/20 | 0.51 |
| ▸ | POLB | P06746 | 1/20 | 0.51 |
| ▸ | PRKCA | P17252 | 2/20 | 0.47 |
| ▸ | ABL1 | P00519 | 2/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.46 |
| ▸ | TMIGD3 | P0DMS9 | 1/20 | 0.46 |
| ▸ | HTR2C | P28335 | 1/20 | 0.46 |
| ▸ | HTR2B | P41595 | 1/20 | 0.46 |
| ▸ | CCR2 | P41597 | 1/20 | 0.45 |
| ▸ | CCR5 | P51681 | 1/20 | 0.45 |
| ▸ | APP | P05067 | 1/20 | 0.44 |
| ▸ | GRM4 | Q14833 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26035496 | 0.93 | MAPT (0.57) | EGFRCDK1SRCMAPTSMN1; SMN2 | |
| SCHEMBL26035023 | 0.89 | MAPT (0.69) | EGFRCDK1SRCMAPTSMN1; SMN2 | |
| SCHEMBL3056423 | 0.87 | TP53 (0.63) | EGFRMAPTSMN1; SMN2TP53POLB | |
| SCHEMBL26035520 | 0.84 | MAPT (0.48) | EGFRCDK1SRCMAPTSMN1; SMN2 | |
| SCHEMBL26035098 | 0.82 | MAPT (0.51) | EGFRCDK1MAPTSMN1; SMN2TP53 | |
| SCHEMBL26035418 | 0.82 | TP53 (0.51) | EGFRCDK1MAPTSMN1; SMN2TP53 | |
| SCHEMBL26035083 | 0.81 | TP53 (0.50) | EGFRCDK1MAPTSMN1; SMN2TP53 | |
| SCHEMBL26035478 | 0.81 | TP53 (0.53) | EGFRMAPTSMN1; SMN2TP53POLB | |
| SCHEMBL26035373 | 0.81 | TP53 (0.49) | EGFRMAPTSMN1; SMN2TP53POLB | |
| SCHEMBL26035100 | 0.81 | TP53 (0.49) | CDK1MAPTSMN1; SMN2TP53POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023159248-A1 | RE-SENSITIZING MULTIDRUG-RESISTANT (MDR) GRAM-NEGATIVE BACTERIA TO COLISTIN USING IONOPHORES | THE REGENTS OF THE UNIVERSITY OF COLORADO A BODY CORPORATE (US) | 2023-08-24 | — | — | WO | disclosed |