Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 3/20 | 0.53 |
| ▸ | MAPT | P10636 | 3/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.53 |
| ▸ | POLB | P06746 | 1/20 | 0.53 |
| ▸ | CCR2 | P41597 | 1/20 | 0.47 |
| ▸ | CCR5 | P51681 | 1/20 | 0.47 |
| ▸ | SYK | P43405 | 1/20 | 0.41 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.41 |
| ▸ | CSNK2A2 | P19784 | 1/20 | 0.41 |
| ▸ | CSNK2B | P67870 | 1/20 | 0.41 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.41 |
| ▸ | CSNK2A3 | Q8NEV1 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | FADS1 | O60427 | 4/20 | 0.40 |
| ▸ | EGFR | P00533 | 2/20 | 0.38 |
| ▸ | BRAF | P15056 | 1/20 | 0.38 |
| ▸ | PDE5A | O76074 | 1/20 | 0.38 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.38 |
| ▸ | GRM4 | Q14833 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26035083 | 0.88 | TP53 (0.50) | TP53MAPTSMN1; SMN2POLBCCR2 | |
| SCHEMBL3056423 | 0.85 | TP53 (0.63) | TP53MAPTSMN1; SMN2POLBCCR2 | |
| SCHEMBL26035418 | 0.81 | TP53 (0.51) | TP53MAPTSMN1; SMN2POLBCCR2 | |
| SCHEMBL26035496 | 0.81 | MAPT (0.57) | TP53MAPTSMN1; SMN2POLBCCR2 | |
| SCHEMBL26035098 | 0.81 | MAPT (0.51) | TP53MAPTSMN1; SMN2POLBCCR2 | |
| SCHEMBL26035474 | 0.81 | EGFR (0.54) | TP53MAPTSMN1; SMN2POLBCCR2 | |
| SCHEMBL26035082 | 0.81 | MAPT (0.48) | TP53MAPTSMN1; SMN2POLBCCR2 | |
| SCHEMBL26035373 | 0.80 | TP53 (0.49) | TP53MAPTSMN1; SMN2POLBCCR2 | |
| SCHEMBL26035379 | 0.80 | PRKCQ (0.49) | TP53MAPTSMN1; SMN2POLBCCR2 | |
| SCHEMBL26035100 | 0.80 | TP53 (0.49) | TP53MAPTSMN1; SMN2POLBCCR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023159248-A1 | RE-SENSITIZING MULTIDRUG-RESISTANT (MDR) GRAM-NEGATIVE BACTERIA TO COLISTIN USING IONOPHORES | THE REGENTS OF THE UNIVERSITY OF COLORADO A BODY CORPORATE (US) | 2023-08-24 | — | — | WO | disclosed |