SCHEMBL26036293

SCHEMBL26036293

CCc1ccc(-c2ccc(CC)c(CC)c2)cc1F

nearest known ligand 0.44

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
ESR1 P03372 3/20 0.44
ESR2 Q92731 3/20 0.44
HSD17B1 P14061 2/20 0.38
IDO1 P14902 2/20 0.35
AGXT P21549 2/20 0.35
RIPK1 Q13546 2/20 0.35
RARB P10826 2/20 0.35
RARA P10276 1/20 0.35
RARG P13631 1/20 0.35
MGLL Q99685 1/20 0.34
ALOX5AP P20292 1/20 0.34
FEN1 P39748 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15471657 0.93 ESR1 (0.46) ESR1ESR2HSD17B1RARBRARA
SCHEMBL10916725 0.86 HSD17B1 (0.45) ESR1ESR2HSD17B1
SCHEMBL15471654 0.86 ALOX5AP (0.43) ESR1ESR2HSD17B1RARBALOX5AP
SCHEMBL12603792 0.85 TNKS2 (0.42) ESR1ESR2IDO1AGXTRIPK1
SCHEMBL13762684 0.84 ESR1 (0.40) ESR1ESR2HSD17B1IDO1AGXT
SCHEMBL26036294 0.84 ESR1 (0.43) ESR1ESR2HSD17B1IDO1AGXT
SCHEMBL17859649 0.83 FFAR1 (0.43) ESR1ESR2RARBRARARARG
SCHEMBL15471662 0.83 RARB (0.43) ESR1ESR2RARBRARARARG
SCHEMBL14329412 0.83 RARB (0.43) ESR1ESR2RARBRARARARG
SCHEMBL19116980 0.82 ESR1 (0.41) ESR1ESR2RARBRARARARG

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11739270-B2 Polymerizable compound as well as liquid crystal composition and liquid crystal display device each including polymerizable compound DIC CORPORATION (JP) 2023-08-29 US disclosed
US-20230131540-A1 LIQUID CRYSTAL COMPOSITION, LIQUID CRYSTAL DISPLAY ELEMENT AND COMPOUND DIC CORPORATION (JP) 2023-04-27 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11739270-B2 Polymerizable compound as well as liquid crystal composition and liquid crystal display device each including polymerizable compound OCIAD2, PKN2, SKP1 ESR1 3415/4885ESR2 3116/4885HSD17B1 1418/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.