Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4C | Q9H3R0 | 20/20 | 0.45 |
| ▸ | KDM5A | P29375 | 2/20 | 0.45 |
| ▸ | KDM5B | Q9UGL1 | 2/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25135375 | 0.86 | KDM4C (0.38) | KDM4CKDM5AKDM5B | |
| SCHEMBL26036636 | 0.85 | KDM4C (0.35) | KDM4CKDM5AKDM5B | |
| SCHEMBL19972616 | 0.83 | SMN1; SMN2 (0.49) | — | |
| SCHEMBL25135208 | 0.73 | GPR6 (0.32) | KDM4C | |
| SCHEMBL19972692 | 0.69 | KDM4C (0.41) | KDM4CKDM5AKDM5B | |
| SCHEMBL19972684 | 0.68 | KDM4C (0.40) | KDM4CKDM5AKDM5B | |
| SCHEMBL26036581 | 0.67 | RORC (0.34) | KDM4CKDM5AKDM5B | |
| SCHEMBL14875496 | 0.67 | AOC3 (0.48) | KDM4C | |
| SCHEMBL14875672 | 0.67 | AOC3 (0.43) | — | |
| SCHEMBL31001701 | 0.66 | MAPT (0.53) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11739085-B2 | Inhibitors of the menin-MLL interaction | VITAE PHARMACEUTICALS, LLC (US) | 2023-08-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11739085-B2 | Inhibitors of the menin-MLL interaction | MLLT1, MEN1, MLLT3 | KDM4C 397/4885KDM5A 249/4885KDM5B 185/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.