Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FOLH1 | Q04609 | 1/20 | 0.63 |
| ▸ | EPHX2 | P34913 | 7/20 | 0.32 |
| ▸ | PPARG | P37231 | 4/20 | 0.32 |
| ▸ | CPB2 | Q96IY4 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24023410 | 0.93 | FOLH1 (0.74) | FOLH1PPARG | |
| SCHEMBL20179142 | 0.86 | FOLH1 (0.72) | FOLH1EPHX2PPARG | |
| SCHEMBL20179256 | 0.82 | FOLH1 (0.80) | FOLH1PPARG | |
| SCHEMBL24023462 | 0.80 | FOLH1 (0.39) | FOLH1EPHX2PPARGCPB2 | |
| SCHEMBL20179133 | 0.80 | FOLH1 (0.82) | FOLH1EPHX2PPARG | |
| SCHEMBL20168739 | 0.79 | FOLH1 (0.66) | FOLH1 | |
| SCHEMBL21578051 | 0.78 | FOLH1 (0.75) | FOLH1 | |
| SCHEMBL20179144 | 0.77 | FOLH1 (0.68) | FOLH1 | |
| SCHEMBL21570573 | 0.77 | FOLH1 (0.80) | FOLH1 | |
| SCHEMBL21577992 | 0.76 | FOLH1 (0.65) | FOLH1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023154939-A2 | GCPII INHIBITION FOR THE TREATMENT OF SARCOPENIA AND AGING | THE JOHNS HOPKINS UNIVERSITY (US) | 2023-08-17 | — | — | WO | disclosed |