Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 11/20 | 0.51 |
| ▸ | RAB9A | P51151 | 10/20 | 0.51 |
| ▸ | AR | P10275 | 3/20 | 0.51 |
| ▸ | MEN1 | O00255 | 2/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 7/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.51 |
| ▸ | NFKB1 | P19838 | 3/20 | 0.51 |
| ▸ | NFKB2 | Q00653 | 3/20 | 0.51 |
| ▸ | RELA | Q04206 | 3/20 | 0.51 |
| ▸ | MAPT | P10636 | 4/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.50 |
| ▸ | HPGD | P15428 | 2/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | GMNN | O75496 | 1/20 | 0.50 |
| ▸ | TP53 | P04637 | 1/20 | 0.50 |
| ▸ | PKM | P14618 | 1/20 | 0.50 |
| ▸ | THPO | P40225 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15397046 | 0.90 | NPC1 (0.59) | NPC1RAB9AARMEN1KMT2A | |
| SCHEMBL18845434 | 0.89 | NPC1 (0.45) | NPC1RAB9AARMEN1KMT2A | |
| SCHEMBL17343409 | 0.89 | NPC1 (0.45) | NPC1RAB9AARMEN1KMT2A | |
| SCHEMBL34467584 | 0.88 | NPC1 (0.63) | NPC1RAB9AARMEN1KMT2A | |
| SCHEMBL240431 | 0.88 | NPC1 (0.63) | NPC1RAB9AARMEN1KMT2A | |
| SCHEMBL17343466 | 0.87 | NPC1 (0.44) | NPC1RAB9AARMEN1KMT2A | |
| SCHEMBL17343363 | 0.87 | NPC1 (0.47) | NPC1RAB9AARMEN1KMT2A | |
| SCHEMBL18934214 | 0.86 | EGFR (0.47) | NPC1RAB9AARMEN1KMT2A | |
| SCHEMBL21191522 | 0.86 | PIK3CD (0.57) | NPC1RAB9AARMEN1KMT2A | |
| SCHEMBL25463657 | 0.86 | NPC1 (0.48) | NPC1RAB9AARMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230271949-A1 | GLP-1R MODULATING COMPOUNDS | ASCLETIS BIOSCIENCE CO., LTD. (CN) | 2023-08-31 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230271949-A1 | GLP-1R MODULATING COMPOUNDS | GLP1R, GIPR, GPR119 | NPC1 1714/4885RAB9A 592/4885AR 1369/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.