SCHEMBL26040604

SCHEMBL26040604

Cc1cc(C(C)N)c2ncn(C)c(=O)c2c1

nearest known ligand 0.50

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
F2RL3 Q96RI0 4/20 0.49
L3MBTL1 Q9Y468 1/20 0.34
SYK P43405 2/20 0.33
IP6K1 Q92551 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31473557 0.85 F2RL3 (0.49) F2RL3L3MBTL1SYKIP6K1
SCHEMBL22306189 0.78 F2RL3 (0.56) F2RL3L3MBTL1IP6K1
SCHEMBL25362190 0.77 AKT1 (0.36) F2RL3
SCHEMBL25362189 0.77 AKT1 (0.36) F2RL3
SCHEMBL30495185 0.76 AKT1 (0.33) F2RL3
SCHEMBL20299339 0.75 F2RL3 (0.54) F2RL3L3MBTL1IP6K1
SCHEMBL26041244 0.75 F2RL3 (0.57) F2RL3L3MBTL1IP6K1
Hydrochloric Acid SCHEMBL25360553 0.75 AKT1 (0.33) F2RL3
Hydrochloric Acid SCHEMBL25361513 0.75 AKT1 (0.33) F2RL3
SCHEMBL30495193 0.75 F2RL3 (0.41) F2RL3L3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2023159155-A1 INHIBITORS OF PHOSPHOINOSITIDE 3-KINASE (PI3K) AND USES THEREOF PIVALENT THERAPEUTICS, INC. (US) 2023-08-24 WO disclosed