Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F2RL3 | Q96RI0 | 4/20 | 0.57 |
| ▸ | EGFR | P00533 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | IP6K1 | Q92551 | 1/20 | 0.35 |
| ▸ | BRD9 | Q9H8M2 | 1/20 | 0.34 |
| ▸ | BRD7 | Q9NPI1 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22306189 | 0.83 | F2RL3 (0.56) | F2RL3L3MBTL1IP6K1 | |
| SCHEMBL20299339 | 0.80 | F2RL3 (0.54) | F2RL3L3MBTL1IP6K1KDM4E | |
| SCHEMBL25358216 | 0.76 | F2RL3 (0.53) | F2RL3L3MBTL1IP6K1KDM4E | |
| SCHEMBL31559877 | 0.75 | F2RL3 (0.40) | F2RL3EGFRL3MBTL1IP6K1KDM4E | |
| SCHEMBL3758387 | 0.75 | C1S (0.38) | F2RL3L3MBTL1KDM4E | |
| SCHEMBL31473557 | 0.75 | F2RL3 (0.49) | F2RL3L3MBTL1IP6K1KDM4E | |
| SCHEMBL26040604 | 0.75 | F2RL3 (0.49) | F2RL3L3MBTL1IP6K1 | |
| SCHEMBL15519338 | 0.75 | F2RL3 (0.36) | F2RL3L3MBTL1IP6K1BRD9BRD7 | |
| SCHEMBL15518793 | 0.75 | ACVR1 (0.42) | F2RL3L3MBTL1IP6K1 | |
| SCHEMBL25360627 | 0.73 | EGFR (0.53) | F2RL3EGFRL3MBTL1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023159155-A1 | INHIBITORS OF PHOSPHOINOSITIDE 3-KINASE (PI3K) AND USES THEREOF | PIVALENT THERAPEUTICS, INC. (US) | 2023-08-24 | — | — | WO | disclosed |