Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | BRD4 | O60885 | 1/20 | 0.36 |
| ▸ | MMP2 | P08253 | 1/20 | 0.36 |
| ▸ | ANPEP | P15144 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | CCKBR | P32239 | 1/20 | 0.34 |
| ▸ | PDE5A | O76074 | 3/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24346570 | 1.00 | KDM4E (0.40) | KDM4EHSD17B10TSHRHTTKMT2A | |
| SCHEMBL24346569 | 1.00 | KDM4E (0.40) | KDM4EHSD17B10TSHRHTTKMT2A | |
| SCHEMBL26041476 | 1.00 | KDM4E (0.40) | KDM4EHSD17B10TSHRHTTKMT2A | |
| SCHEMBL3072000 | 0.88 | KMT2A (0.43) | KDM4EHSD17B10TSHRHTTKMT2A | |
| SCHEMBL3072002 | 0.88 | KMT2A (0.43) | KDM4EHSD17B10TSHRHTTKMT2A | |
| SCHEMBL3072005 | 0.81 | KMT2A (0.41) | KDM4EHSD17B10TSHRHTTKMT2A | |
| SCHEMBL25370397 | 0.79 | CYP2D6 (0.41) | KDM4ETSHRHTTKMT2AALDH1A1 | |
| SCHEMBL23002166 | 0.79 | CYP2D6 (0.41) | KDM4ETSHRHTTKMT2AALDH1A1 | |
| SCHEMBL16635019 | 0.76 | — | — | |
| SCHEMBL202780 | 0.73 | ALDH1A1 (0.48) | KDM4EHSD17B10TSHRHTTKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4223368-A1 | MACROCYCLE COMPOUND | Asahi Kasei Pharma Corporation (JP) | 2023-08-09 | — | — | EP | disclosed |