Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.50 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | THRB | P10828 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | CES2 | O00748 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
| ▸ | NOS3 | P29474 | 1/20 | 0.33 |
| ▸ | NOS1 | P29475 | 1/20 | 0.33 |
| ▸ | NOS2 | P35228 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.33 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.33 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.33 |
| ▸ | USP2 | O75604 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10298186 | 0.76 | TSHR (0.50) | TSHRMEN1KMT2ATHRBHTT | |
| SCHEMBL5690898 | 0.75 | TSHR (0.52) | TSHRMEN1KMT2ATHRBHTT | |
| SCHEMBL6655170 | 0.75 | — | — | |
| Hydrogen Peroxide SCHEMBL28446111 | 0.74 | TSHR (0.72) | TSHRMEN1KMT2ATHRBHTT | |
| Methyl Alcohol SCHEMBL2390958 | 0.74 | TSHR (0.72) | TSHRMEN1KMT2ATHRBHTT | |
| SCHEMBL15167 | 0.74 | — | — | |
| SCHEMBL8600029 | 0.74 | TSHR (0.71) | TSHRMEN1KMT2ATHRBHTT | |
| SCHEMBL439119 | 0.74 | TSHR (0.71) | TSHRMEN1KMT2ATHRBHTT | |
| SCHEMBL28748446 | 0.74 | TSHR (0.71) | TSHRMEN1KMT2ATHRBHTT | |
| SCHEMBL5932549 | 0.73 | TSHR (0.50) | TSHRMEN1KMT2ATHRBHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4234550-A2 | METHODS AND COMPOUNDS FOR THE TREATMENT OF GENETIC DISEASE | Design Therapeutics, Inc. (US) | 2023-08-30 | — | — | EP | disclosed |