SCHEMBL260429

SCHEMBL260429

NC(=S)Nc1cccc2ccccc12

nearest known ligand 0.71

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 5/20 0.71
KMT2A Q03164 4/20 0.71
GAA P10253 3/20 0.71
ALDH1A1 P00352 3/20 0.71
SMN1; SMN2 Q16637 3/20 0.71
MEN1 O00255 3/20 0.71
MAPT P10636 2/20 0.71
CYP1A2 P05177 4/20 0.62
CYP3A4 P08684 4/20 0.62
CYP2C19 P33261 3/20 0.62
CYP2D6 P10635 2/20 0.62
CYP2C9 P11712 2/20 0.62
ALOX12 P18054 1/20 0.62
SIGMAR1 Q99720 2/20 0.57
GRIN2D O15399 1/20 0.57
GRIN3B O60391 1/20 0.57
GRIN1 Q05586 1/20 0.57
GRIN2A Q12879 1/20 0.57
GRIN2B Q13224 1/20 0.57
GRIN2C Q14957 1/20 0.57

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29522175 1.00 KDM4E (0.71) KDM4EKMT2AGAAALDH1A1SMN1; SMN2
Hydrogen Sulfide SCHEMBL27456819 0.98 KDM4E (0.69) KDM4EKMT2AGAAALDH1A1SMN1; SMN2
Hydrazine SCHEMBL28848708 0.98 KDM4E (0.69) KDM4EKMT2AGAAALDH1A1SMN1; SMN2
SCHEMBL27567335 0.98 KDM4E (0.69) KDM4EKMT2AGAAALDH1A1SMN1; SMN2
Trimethylammonium SCHEMBL27986322 0.93 KDM4E (0.63) KDM4EKMT2AGAAALDH1A1SMN1; SMN2
SCHEMBL17281502 0.87 ALDH1A1 (0.63) KDM4EKMT2AGAAALDH1A1SMN1; SMN2
SCHEMBL9724986 0.86 KDM4E (0.67) KDM4EKMT2AGAAALDH1A1SMN1; SMN2
SCHEMBL1275812 0.83 KMT2A (0.72) KDM4EKMT2AGAAALDH1A1SMN1; SMN2
SCHEMBL1741823 0.82 KDM4E (0.71) KDM4EKMT2AGAAALDH1A1SMN1; SMN2
SCHEMBL30227787 0.82 KDM4E (0.71) KDM4EKMT2AGAAALDH1A1SMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 662 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3816325-B1 ACIDIC AQUEOUS SILVER-NICKEL ALLOY ELECTROPLATING COMPOSITIONS AND METHODS DUPONT ELECTRONIC MAT INTERNATIONAL LLC (US) 2025-05-07 EP claimed
CN-115449136-B Accelerator composition of rubber nanocomposite as well as preparation method and application thereof 浙江大学 2024-02-27 CN claimed
CN-115160995-B Viscosity reducer for drilling fluid and preparation method thereof 山东诺尔生物科技有限公司 2023-08-04 CN claimed
CN-115449136-A Accelerator composition of rubber nanocomposite and preparation method and application thereof 浙江大学 2022-12-09 CN claimed
CN-115160995-A Viscosity reducer for drilling fluid and preparation method thereof 山东诺尔生物科技有限公司 2022-10-11 CN claimed
EP-3695723-A1 VERMIN CONTROL COMPOSITIONS Goode, Steven (GB) 2020-08-19 EP claimed
CN-110697703-A Leaching of superhard materials by enhanced demetallization 哈里伯顿能源服务公司 2020-01-17 CN claimed
US-20180027807-A1 Vermin Control Compositions GOODE STEVEN (US) 2018-02-01 US claimed
CN-107630238-A Indium electroplating compositions and the method for indium plating 罗门哈斯电子材料有限责任公司 2018-01-26 CN claimed
EP-3272909-A1 INDIUM ELECTROPLATING COMPOSITIONS AND METHODS FOR ELECTROPLATING INDIUM Rohm and Haas Electronic Materials LLC (US) 2018-01-24 EP claimed
EP-1198232-A4 UREA SUBSTITUTED IMIDAZOQUINOLINES 3M INNOVATIVE PROPERTIES CO (US) 2002-07-24 EP claimed
CN-1355701-A Urea substituted imidazoquinolines 3M INNOVATIVE PROPERTIES CO (US) 2002-06-26 CN claimed
EP-1198232-A1 UREA SUBSTITUTED IMIDAZOQUINOLINES 3M Innovative Properties Company (US) 2002-04-24 EP claimed
CN-1323215-A Inhibition of toxic materials or substances using dendrimers STARPHARMA LTD (AU) 2001-11-21 CN claimed
CN-1323214-A Antimicrobial or antiparasitic compositions of anionic or cationic dendrimers STARPHARMA LTD (AU) 2001-11-21 CN claimed
EP-1118322-A1 DRUGS FOR IMPROVING VESICAL EXCRETORY STRENGTH Takeda Chemical Industries, Ltd. (JP) 2001-07-25 EP claimed
WO-2000076518-A1 UREA SUBSTITUTED IMIDAZOQUINOLINES 3M INNOVATIVE PROPERTIES COMPANY (US) 2000-12-21 WO claimed
EP-0594653-A1 RODENT BAIT PACKAGE ZENECA LIMITED (GB) 1994-05-04 EP claimed
WO-1993001712-A1 RODENT BAIT PACKAGE ZENECA LIMITED (GB) 1993-02-04 WO claimed
US-4421344-A THIOUREA, AND ZINC OXIDE OR HYDROXIDE TO PREVENT FADING OJI PAPER CO., LTD. (JP) 1983-12-20 US claimed