SCHEMBL2604419

SCHEMBL2604419

CC(C)(C)c1ccc2c(c1)C(C)(C)c1cc(C(C)(C)C)ccc1N2c1ccc2c3ccc(N4c5ccc(C(C)(C)C)cc5C(C)(C)c5cc(C(C)(C)C)ccc54)cc3n(-c3ccc4c(c3)C(C)(C)c3ccccc3-4)c2c1

nearest known ligand 0.32

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
NPC1 O15118 1/20 0.32
ALDH1A1 P00352 1/20 0.32
PLA2G1B P04054 1/20 0.32
NFKB1 P19838 1/20 0.32
CASP3 P42574 1/20 0.32
RAB9A P51151 1/20 0.32
NFKB2 Q00653 1/20 0.32
RELA Q04206 1/20 0.32
SENP8 Q96LD8 1/20 0.32
SENP7 Q9BQF6 1/20 0.32
SENP6 Q9GZR1 1/20 0.32
L3MBTL1 Q9Y468 1/20 0.32
ATG4B Q9Y4P1 1/20 0.32
PGR P06401 1/20 0.30
NR1H3 Q13133 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17774067 0.94 NPC1 (0.32) NPC1ALDH1A1PLA2G1BNFKB1CASP3
SCHEMBL2604418 0.93 NPC1 (0.32) NPC1ALDH1A1PLA2G1BNFKB1CASP3
SCHEMBL2604411 0.88 NPC1 (0.35) NPC1ALDH1A1PLA2G1BNFKB1CASP3
SCHEMBL2604417 0.87 KDM4E (0.34) L3MBTL1
SCHEMBL2604415 0.85 POLB (0.33) ALDH1A1
SCHEMBL15788347 0.85 NPSR1 (0.30)
SCHEMBL16547119 0.85 KDM4E (0.33) ALDH1A1L3MBTL1
SCHEMBL2604414 0.84 POLB (0.31)
SCHEMBL10134263 0.82 ALDH1A1 (0.32) ALDH1A1
SCHEMBL2604393 0.82 NPC1 (0.37) NPC1ALDH1A1PLA2G1BNFKB1CASP3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8860016-B2 Photoelectric conversion device and imaging device FUJIFILM CORPORATION (JP) 2014-10-14 US disclosed
US-8860016-B2 Photoelectric conversion device and imaging device FUJIFILM CORPORATION (JP) 2014-10-14 US disclosed
US-8704213-B2 Photoelectric conversion device and solid-state imaging FUJIFILM CORPORATION (JP) 2014-04-22 US disclosed
US-8704213-B2 Photoelectric conversion device and solid-state imaging FUJIFILM CORPORATION (JP) 2014-04-22 US disclosed
US-8513657-B2 Photoelectric conversion element and solid-state imaging device FUJIFILM CORPORATION (JP) 2013-08-20 US disclosed
US-8513657-B2 Photoelectric conversion element and solid-state imaging device FUJIFILM CORPORATION (JP) 2013-08-20 US disclosed
US-20130020566-A1 PHOTOELECTRIC CONVERSION DEVICE AND IMAGING DEVICE FUJIFILM CORPORATION (JP) 2013-01-24 US disclosed
US-20130020566-A1 PHOTOELECTRIC CONVERSION DEVICE AND IMAGING DEVICE FUJIFILM CORPORATION (JP) 2013-01-24 US disclosed
US-20120098079-A1 PHOTOELECTRIC CONVERSION DEVICE AND SOLID-STATE IMAGING DEVICE FUJIFILM CORPORATION (JP) 2012-04-26 US disclosed
US-20120098079-A1 PHOTOELECTRIC CONVERSION DEVICE AND SOLID-STATE IMAGING DEVICE FUJIFILM CORPORATION (JP) 2012-04-26 US disclosed
US-20110194000-A1 PHOTOELECTRIC CONVERSION ELEMENT AND SOLID-STATE IMAGING DEVICE FUJIFILM CORPORATION (JP) 2011-08-11 US disclosed
US-20110194000-A1 PHOTOELECTRIC CONVERSION ELEMENT AND SOLID-STATE IMAGING DEVICE FUJIFILM CORPORATION (JP) 2011-08-11 US disclosed