SCHEMBL2604420

SCHEMBL2604420

CC(C)(C)c1ccc2c(c1)C(C)(C)c1cc(C(C)(C)C)ccc1N2c1ccc2c(c1)c1cc(N3c4ccc(C(C)(C)C)cc4C(C)(C)c4cc(C(C)(C)C)ccc43)ccc1n2-c1ccc2ccccc2c1

nearest known ligand 0.34

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
POLB P06746 1/20 0.34
KMT2A Q03164 1/20 0.34
HSP90AA1 P07900 1/20 0.33
ALDH1A1 P00352 1/20 0.32
LMNA P02545 1/20 0.32
CYP1A2 P05177 1/20 0.32
CYP2C9 P11712 1/20 0.32
HPGD P15428 1/20 0.32
CYP2C19 P33261 1/20 0.32
KCNH2 Q12809 1/20 0.31
MAPK9 P45984 1/20 0.30
MAPK10 P53779 1/20 0.30
PPARG P37231 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2604412 0.97 POLB (0.31) POLBKMT2AHSP90AA1KCNH2
SCHEMBL2604415 0.92 POLB (0.33) POLBKMT2AHSP90AA1ALDH1A1LMNA
SCHEMBL2604414 0.89 POLB (0.31) POLBKMT2A
SCHEMBL2604408 0.88 KDM4E (0.35) KCNH2PPARG
SCHEMBL15118499 0.87 KMT2A (0.37) POLBKMT2AHSP90AA1ALDH1A1LMNA
SCHEMBL2604418 0.84 NPC1 (0.32) ALDH1A1
SCHEMBL15118498 0.83 CYP1A2 (0.41) POLBKMT2AHSP90AA1ALDH1A1LMNA
SCHEMBL2604407 0.83 KCNH2 (0.39) POLBKMT2AHSP90AA1ALDH1A1CYP1A2
SCHEMBL15119779 0.81 HSP90AA1 (0.35) POLBKMT2AHSP90AA1ALDH1A1LMNA
SCHEMBL2604417 0.80 KDM4E (0.34) PPARG

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8860016-B2 Photoelectric conversion device and imaging device FUJIFILM CORPORATION (JP) 2014-10-14 US disclosed
US-8860016-B2 Photoelectric conversion device and imaging device FUJIFILM CORPORATION (JP) 2014-10-14 US disclosed
US-8704213-B2 Photoelectric conversion device and solid-state imaging FUJIFILM CORPORATION (JP) 2014-04-22 US disclosed
US-8704213-B2 Photoelectric conversion device and solid-state imaging FUJIFILM CORPORATION (JP) 2014-04-22 US disclosed
US-8513657-B2 Photoelectric conversion element and solid-state imaging device FUJIFILM CORPORATION (JP) 2013-08-20 US disclosed
US-8513657-B2 Photoelectric conversion element and solid-state imaging device FUJIFILM CORPORATION (JP) 2013-08-20 US disclosed
US-20130020566-A1 PHOTOELECTRIC CONVERSION DEVICE AND IMAGING DEVICE FUJIFILM CORPORATION (JP) 2013-01-24 US disclosed
US-20130020566-A1 PHOTOELECTRIC CONVERSION DEVICE AND IMAGING DEVICE FUJIFILM CORPORATION (JP) 2013-01-24 US disclosed
US-20120098079-A1 PHOTOELECTRIC CONVERSION DEVICE AND SOLID-STATE IMAGING DEVICE FUJIFILM CORPORATION (JP) 2012-04-26 US disclosed
US-20120098079-A1 PHOTOELECTRIC CONVERSION DEVICE AND SOLID-STATE IMAGING DEVICE FUJIFILM CORPORATION (JP) 2012-04-26 US disclosed
US-20110194000-A1 PHOTOELECTRIC CONVERSION ELEMENT AND SOLID-STATE IMAGING DEVICE FUJIFILM CORPORATION (JP) 2011-08-11 US disclosed
US-20110194000-A1 PHOTOELECTRIC CONVERSION ELEMENT AND SOLID-STATE IMAGING DEVICE FUJIFILM CORPORATION (JP) 2011-08-11 US disclosed