SCHEMBL2604408

SCHEMBL2604408

CC(C)(C)c1ccc2c(c1)C(C)(C)c1cc(C(C)(C)C)ccc1N2c1ccc2c(c1)c1cc(N3c4ccc(C(C)(C)C)cc4C(C)(C)c4cc(C(C)(C)C)ccc43)ccc1n2-c1ccccc1

nearest known ligand 0.35

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 1/20 0.35
ATM Q13315 1/20 0.35
L3MBTL1 Q9Y468 1/20 0.35
PPARG P37231 8/20 0.34
PPARA Q07869 2/20 0.32
KCNH2 Q12809 1/20 0.31
NR1H4 Q96RI1 1/20 0.31
TEAD1 P28347 1/20 0.31
TEAD4 Q15561 1/20 0.31
TEAD2 Q15562 1/20 0.31
TEAD3 Q99594 1/20 0.31
MDM2 Q00987 1/20 0.31
DNMT1 P26358 3/20 0.31
PGR P06401 1/20 0.30
RORA P35398 1/20 0.30
RORC P51449 1/20 0.30
RORB Q92753 1/20 0.30
TSHR P16473 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2604417 0.91 KDM4E (0.34) KDM4EATML3MBTL1PPARGPPARA
SCHEMBL2604420 0.88 POLB (0.34) PPARGKCNH2
SCHEMBL2604412 0.87 POLB (0.31) KCNH2
SCHEMBL2604418 0.86 NPC1 (0.32) L3MBTL1PGR
SCHEMBL20408093 0.85 PGR (0.37) L3MBTL1PGRTSHR
SCHEMBL12333423 0.85 NPSR1 (0.34) KDM4EATML3MBTL1PPARGPPARA
SCHEMBL10134263 0.84 ALDH1A1 (0.32)
SCHEMBL13231642 0.84 KDM4E (0.41) KDM4EATML3MBTL1PGRTSHR
SCHEMBL16547119 0.83 KDM4E (0.33) KDM4EATML3MBTL1PPARG
SCHEMBL13231450 0.82 AR (0.33) L3MBTL1PGRTSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8860016-B2 Photoelectric conversion device and imaging device FUJIFILM CORPORATION (JP) 2014-10-14 US disclosed
US-8860016-B2 Photoelectric conversion device and imaging device FUJIFILM CORPORATION (JP) 2014-10-14 US disclosed
US-8704213-B2 Photoelectric conversion device and solid-state imaging FUJIFILM CORPORATION (JP) 2014-04-22 US disclosed
US-8704213-B2 Photoelectric conversion device and solid-state imaging FUJIFILM CORPORATION (JP) 2014-04-22 US disclosed
US-8513657-B2 Photoelectric conversion element and solid-state imaging device FUJIFILM CORPORATION (JP) 2013-08-20 US disclosed
US-8513657-B2 Photoelectric conversion element and solid-state imaging device FUJIFILM CORPORATION (JP) 2013-08-20 US disclosed
US-20130020566-A1 PHOTOELECTRIC CONVERSION DEVICE AND IMAGING DEVICE FUJIFILM CORPORATION (JP) 2013-01-24 US disclosed
US-20130020566-A1 PHOTOELECTRIC CONVERSION DEVICE AND IMAGING DEVICE FUJIFILM CORPORATION (JP) 2013-01-24 US disclosed
US-20120098079-A1 PHOTOELECTRIC CONVERSION DEVICE AND SOLID-STATE IMAGING DEVICE FUJIFILM CORPORATION (JP) 2012-04-26 US disclosed
US-20120098079-A1 PHOTOELECTRIC CONVERSION DEVICE AND SOLID-STATE IMAGING DEVICE FUJIFILM CORPORATION (JP) 2012-04-26 US disclosed
US-20110194000-A1 PHOTOELECTRIC CONVERSION ELEMENT AND SOLID-STATE IMAGING DEVICE FUJIFILM CORPORATION (JP) 2011-08-11 US disclosed
US-20110194000-A1 PHOTOELECTRIC CONVERSION ELEMENT AND SOLID-STATE IMAGING DEVICE FUJIFILM CORPORATION (JP) 2011-08-11 US disclosed