SCHEMBL2604423

SCHEMBL2604423

CC(C)(C)c1ccc2c(c1)c1cc(C(C)(C)C)ccc1n2-c1ccc2c3cc(-c4ccc5c(c4)c4ccc(-n6c7ccc(C(C)(C)C)cc7c7cc(C(C)(C)C)ccc76)cc4n5-c4ccccc4)ccc3n(-c3ccccc3)c2c1

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 1/20 0.42
ATM Q13315 1/20 0.42
L3MBTL1 Q9Y468 1/20 0.42
PPARG P37231 4/20 0.36
ALDH1A1 P00352 1/20 0.36
MAPT P10636 1/20 0.36
MAPK1 P28482 1/20 0.36
NPSR1 Q6W5P4 1/20 0.36
PTGES O14684 1/20 0.36
SERPINE1 P05121 1/20 0.35
PGR P06401 1/20 0.35
RORA P35398 1/20 0.35
RORC P51449 1/20 0.35
RORB Q92753 1/20 0.35
DNMT1 P26358 3/20 0.35
MAT2A P31153 1/20 0.35
KIF11 P52732 2/20 0.35
PPARA Q07869 2/20 0.34
NOTUM Q6P988 1/20 0.34
OPRD1 P41143 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16171497 0.97 KDM4E (0.47) KDM4EATML3MBTL1PPARGALDH1A1
SCHEMBL12394526 0.97 KDM4E (0.42) KDM4EATML3MBTL1PPARGALDH1A1
SCHEMBL16171526 0.96 KDM4E (0.46) KDM4EATML3MBTL1PPARGALDH1A1
SCHEMBL15445762 0.95 KDM4E (0.47) KDM4EATML3MBTL1PPARGALDH1A1
SCHEMBL2604397 0.94 KDM4E (0.47) KDM4EATML3MBTL1PPARGPGR
SCHEMBL16171528 0.93 KDM4E (0.46) KDM4EATML3MBTL1PPARGALDH1A1
SCHEMBL15445964 0.93 KDM4E (0.49) KDM4EATML3MBTL1PPARGALDH1A1
SCHEMBL18267238 0.93 KDM4E (0.40) KDM4EATML3MBTL1PPARGALDH1A1
SCHEMBL15469165 0.93 KDM4E (0.42) KDM4EATML3MBTL1PPARGALDH1A1
SCHEMBL15445864 0.92 KDM4E (0.47) KDM4EATML3MBTL1PPARGALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8704213-B2 Photoelectric conversion device and solid-state imaging FUJIFILM CORPORATION (JP) 2014-04-22 US disclosed
US-8704213-B2 Photoelectric conversion device and solid-state imaging FUJIFILM CORPORATION (JP) 2014-04-22 US disclosed
US-20120098079-A1 PHOTOELECTRIC CONVERSION DEVICE AND SOLID-STATE IMAGING DEVICE FUJIFILM CORPORATION (JP) 2012-04-26 US disclosed
US-20120098079-A1 PHOTOELECTRIC CONVERSION DEVICE AND SOLID-STATE IMAGING DEVICE FUJIFILM CORPORATION (JP) 2012-04-26 US disclosed