SCHEMBL15445964

SCHEMBL15445964

CC(C)(C)c1ccc(-n2c3ccccc3c3cc(-c4ccc5c(c4)c4ccccc4n5-c4ccc5c6ccccc6n(-c6ccccc6)c5c4)ccc32)cc1

nearest known ligand 0.49

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 1/20 0.49
ATM Q13315 1/20 0.49
L3MBTL1 Q9Y468 1/20 0.49
PPARG P37231 4/20 0.42
ALDH1A1 P00352 1/20 0.42
MAPT P10636 1/20 0.42
MAPK1 P28482 1/20 0.42
NPSR1 Q6W5P4 1/20 0.42
PPARA Q07869 2/20 0.40
PTGES O14684 1/20 0.38
PTGER4 P35408 1/20 0.36
KMT2A Q03164 1/20 0.36
TSPO P30536 1/20 0.36
HDAC4 P56524 1/20 0.36
KIF11 P52732 1/20 0.35
NR1H4 Q96RI1 2/20 0.35
PMM2 O15305 1/20 0.35
MPI P34949 1/20 0.35
PHOSPHO1 Q8TCT1 1/20 0.35
OPRD1 P41143 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15445864 0.99 KDM4E (0.47) KDM4EATML3MBTL1PPARGALDH1A1
SCHEMBL15445863 0.96 KDM4E (0.47) KDM4EATML3MBTL1PPARGALDH1A1
SCHEMBL16171497 0.96 KDM4E (0.47) KDM4EATML3MBTL1PPARGALDH1A1
SCHEMBL16171570 0.96 KDM4E (0.50) KDM4EATML3MBTL1PPARGALDH1A1
SCHEMBL15745993 0.96 KDM4E (0.50) KDM4EATML3MBTL1PPARGALDH1A1
SCHEMBL16171526 0.95 KDM4E (0.46) KDM4EATML3MBTL1PPARGALDH1A1
SCHEMBL24790091 0.95 KDM4E (0.49) KDM4EATML3MBTL1PPARGALDH1A1
SCHEMBL16171571 0.95 KDM4E (0.49) KDM4EATML3MBTL1PPARGALDH1A1
SCHEMBL15445987 0.94 KDM4E (0.51) KDM4EATML3MBTL1PPARGALDH1A1
SCHEMBL15745994 0.94 KDM4E (0.55) KDM4EATML3MBTL1PPARGALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10707434-B2 Organic electroluminescence element, and material for organic electroluminescence element IDEMITSU KOSAN CO., LTD. (JP) 2020-07-07 US disclosed
US-20190019972-A1 ORGANIC ELECTROLUMINESCENCE ELEMENT, AND MATERIAL FOR ORGANIC ELECTROLUMINESCENCE ELEMENT IDEMITSU KOSAN CO., LTD. (JP) 2019-01-17 US disclosed
US-9564595-B2 Bis-carbazole derivative and organic electroluminescent element using same IDEMITSU KOSAN CO., LTD. (JP) 2017-02-07 US disclosed
US-9564595-B2 Bis-carbazole derivative and organic electroluminescent element using same IDEMITSU KOSAN CO., LTD. (JP) 2017-02-07 US disclosed
US-20140306207-A1 ORGANIC ELECTROLUMINESCENCE ELEMENT, AND MATERIAL FOR ORGANIC ELECTROLUMINESCENCE ELEMENT IDEMITSU KOSAN CO., LTD. (JP) 2014-10-16 US disclosed
EP-2690093-A1 BIS-CARBAZOLE DERIVATIVE AND ORGANIC ELECTROLUMINESCENT ELEMENT USING SAME Idemitsu Kosan Co., Ltd. (JP) 2014-01-29 EP disclosed
US-20140008633-A1 BIS-CARBAZOLE DERIVATIVE AND ORGANIC ELECTROLUMINESCENT ELEMENT USING SAME MITSUI CHEMICALS, INC (JP) 2014-01-09 US disclosed
US-20140008633-A1 BIS-CARBAZOLE DERIVATIVE AND ORGANIC ELECTROLUMINESCENT ELEMENT USING SAME MITSUI CHEMICALS, INC (JP) 2014-01-09 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20190019972-A1 ORGANIC ELECTROLUMINESCENCE ELEMENT, AND MATERIAL FOR ORGANIC ELECTROLUMINESCENCE ELEMENT LEF1, L1CAM, AGO2 KDM4E 3248/4885ATM 2324/4885L3MBTL1 1678/4885
US-10707434-B2 Organic electroluminescence element, and material for organic electroluminescence element LEF1, L1CAM, AGO2 KDM4E 3248/4885ATM 2324/4885L3MBTL1 1678/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.