SCHEMBL26044858

SCHEMBL26044858

CCOc1ccc(C(=O)C2CCC(CC)CC2)c(F)c1F

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HTT P42858 1/20 0.42
TDP1 Q9NUW8 1/20 0.42
ALDH1A1 P00352 1/20 0.38
BLM P54132 1/20 0.38
CNR1 P21554 1/20 0.37
CNR2 P34972 1/20 0.37
MEN1 O00255 1/20 0.36
UBE2N P61088 1/20 0.36
KMT2A Q03164 1/20 0.36
CYP19A1 P11511 1/20 0.36
SMN1; SMN2 Q16637 2/20 0.36
NPC1 O15118 1/20 0.35
USP2 O75604 1/20 0.35
RAB9A P51151 1/20 0.35
HSD17B10 Q99714 1/20 0.35
RECQL P46063 1/20 0.35
MRGPRX1 Q96LB2 2/20 0.35
TSPO P30536 1/20 0.35
KDM4E B2RXH2 1/20 0.35
GLA P06280 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL26044886 0.96 HTT (0.40) HTTTDP1ALDH1A1BLMCNR1
SCHEMBL26044859 0.91 CNR1 (0.38) HTTTDP1ALDH1A1CNR1CNR2
SCHEMBL26044861 0.90 CCNE2 (0.41) HTTTDP1ALDH1A1CNR1CNR2
SCHEMBL17616205 0.90 HTT (0.41) HTTTDP1ALDH1A1BLMMEN1
SCHEMBL26044862 0.89 CNR1 (0.40) ALDH1A1CNR1CNR2MEN1KMT2A
SCHEMBL26044888 0.88 CNR1 (0.36) HTTTDP1ALDH1A1CNR1CNR2
SCHEMBL26044850 0.88 HTT (0.43) HTTTDP1ALDH1A1BLMMEN1
SCHEMBL26044868 0.87 HTT (0.39) HTTTDP1ALDH1A1BLMCNR2
SCHEMBL26044889 0.87 CCNE2 (0.39) HTTTDP1ALDH1A1CNR1CNR2
SCHEMBL26044891 0.86 HTT (0.39) HTTTDP1ALDH1A1BLMMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230265345-A1 LIQUID CRYSTAL COMPOSITION CONTAINING POLYMERIZABLE COMPOUND AND APPLICATION OF LIQUID CRYSTAL COMPOSITION BEIJING BAYI SPACE LCD TECHNOLOGY CO., LTD. (CN) 2023-08-24 US disclosed