SCHEMBL26044859

SCHEMBL26044859

CCCOc1ccc(C(=O)C2CCC(CC)CC2)c(F)c1F

nearest known ligand 0.38

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CNR1 P21554 2/20 0.38
CNR2 P34972 2/20 0.38
HTT P42858 1/20 0.35
TDP1 Q9NUW8 1/20 0.35
MAPT P10636 3/20 0.34
CCNE2 O96020 1/20 0.34
CCNE1 P24864 1/20 0.34
CDK2 P24941 1/20 0.34
ALDH1A1 P00352 1/20 0.34
NPSR1 Q6W5P4 1/20 0.34
CYP19A1 P11511 1/20 0.34
NTSR1 P30989 1/20 0.34
ATM Q13315 1/20 0.34
ACACB O00763 2/20 0.33
HSD17B10 Q99714 1/20 0.33
HTR2A P28223 2/20 0.33
GRM2 Q14416 1/20 0.33
HTR1A P08908 1/20 0.33
ADRA2A P08913 1/20 0.33
DRD2 P14416 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL26044888 0.96 CNR1 (0.36) CNR1CNR2HTTTDP1MAPT
SCHEMBL26044861 0.94 CCNE2 (0.41) CNR1CNR2HTTTDP1MAPT
SCHEMBL26044862 0.93 CNR1 (0.40) CNR1CNR2MAPTCCNE2CCNE1
SCHEMBL26044864 0.91 CNR1 (0.38) CNR1CNR2HTTTDP1MAPT
SCHEMBL26044858 0.91 HTT (0.42) CNR1CNR2HTTTDP1ALDH1A1
SCHEMBL26044889 0.91 CCNE2 (0.39) CNR1CNR2HTTTDP1MAPT
SCHEMBL26044890 0.90 CNR1 (0.38) CNR1CNR2MAPTCCNE2CCNE1
SCHEMBL26044869 0.89 CCNE2 (0.37) CNR1CNR2HTTMAPTCCNE2
SCHEMBL26044852 0.89 CNR1 (0.39) CNR1CNR2HTTTDP1MAPT
SCHEMBL26044881 0.88 PKM (0.37) CNR1CNR2HTTMAPTCCNE2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230265345-A1 LIQUID CRYSTAL COMPOSITION CONTAINING POLYMERIZABLE COMPOUND AND APPLICATION OF LIQUID CRYSTAL COMPOSITION BEIJING BAYI SPACE LCD TECHNOLOGY CO., LTD. (CN) 2023-08-24 US disclosed