Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 9/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 5/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 2/20 | 0.44 |
| ▸ | HCRTR2 | O43614 | 3/20 | 0.43 |
| ▸ | POLB | P06746 | 2/20 | 0.43 |
| ▸ | HCRTR1 | O43613 | 2/20 | 0.43 |
| ▸ | GPBAR1 | Q8TDU6 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | HTR2C | P28335 | 3/20 | 0.41 |
| ▸ | HTR2A | P28223 | 2/20 | 0.41 |
| ▸ | HTR2B | P41595 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26201767 | 1.00 | KDM4E (0.46) | KDM4EALDH1A1HSD17B10TSHRHPGD | |
| SCHEMBL26046517 | 0.88 | HCRTR2 (0.52) | KDM4EALDH1A1HSD17B10TSHRHPGD | |
| SCHEMBL1672249 | 0.87 | HCRTR2 (0.50) | KDM4EALDH1A1HSD17B10TSHRHPGD | |
| SCHEMBL26046309 | 0.84 | HRH4 (0.47) | KDM4EALDH1A1HSD17B10TSHRHPGD | |
| SCHEMBL30556658 | 0.84 | KDM4E (0.48) | KDM4EALDH1A1HSD17B10TSHRHPGD | |
| SCHEMBL30556681 | 0.79 | HCRTR2 (0.49) | KDM4EALDH1A1HSD17B10TSHRHPGD | |
| SCHEMBL17151435 | 0.78 | DYRK1A (0.50) | KDM4EALDH1A1HSD17B10TSHRHPGD | |
| SCHEMBL29118006 | 0.77 | ROCK2 (0.50) | KDM4EALDH1A1HSD17B10TSHRHPGD | |
| SCHEMBL29118005 | 0.77 | ROCK2 (0.50) | KDM4EALDH1A1HSD17B10TSHRHPGD | |
| SCHEMBL29118052 | 0.77 | ROCK2 (0.50) | KDM4EALDH1A1HSD17B10TSHRHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023164611-A1 | MODULATORS OF MYC FAMILY PROTO-ONCOGENE PROTEIN | NALO THERAPEUTICS (US) | 2023-08-31 | — | — | WO | disclosed |