Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHEK1 | O14757 | 11/20 | 0.44 |
| ▸ | CHEK2 | O96017 | 8/20 | 0.44 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | TSHR | P16473 | 2/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.39 |
| ▸ | GPBAR1 | Q8TDU6 | 1/20 | 0.39 |
| ▸ | SORD | Q00796 | 1/20 | 0.39 |
| ▸ | PDE8B | O95263 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26051217 | 1.00 | CHEK1 (0.44) | CHEK1CHEK2PTPN11MEN1KMT2A | |
| SCHEMBL22119364 | 0.81 | ACACB (0.43) | MEN1KMT2AKDM4EALDH1A1TSHR | |
| SCHEMBL22119365 | 0.81 | ACACB (0.43) | MEN1KMT2AKDM4EALDH1A1TSHR | |
| SCHEMBL26051214 | 0.77 | DKK1 (0.48) | MEN1KMT2AKDM4EALDH1A1TSHR | |
| SCHEMBL26051213 | 0.75 | PDE8B (0.55) | PTPN11MEN1KMT2AKDM4EALDH1A1 | |
| SCHEMBL26047168 | 0.75 | PDE8B (0.55) | PTPN11MEN1KMT2AKDM4EALDH1A1 | |
| SCHEMBL13033008 | 0.74 | KMT2A (0.56) | KMT2AKDM4EALDH1A1TSHRHSD17B10 | |
| SCHEMBL20064225 | 0.70 | HCRTR2 (0.45) | KDM4EALDH1A1TSHRHSD17B10GPBAR1 | |
| SCHEMBL25369355 | 0.70 | PAK4 (0.60) | — | |
| SCHEMBL25370653 | 0.70 | PAK4 (0.60) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023164611-A1 | MODULATORS OF MYC FAMILY PROTO-ONCOGENE PROTEIN | NALO THERAPEUTICS (US) | 2023-08-31 | — | — | WO | disclosed |