SCHEMBL2604754

SCHEMBL2604754

Cc1cc(N(c2ccc(-c3ccccc3)cc2)c2ccc(-c3ccccc3)cc2)ccc1-c1ccc(N(c2ccc(-c3ccccc3)cc2)c2ccc(-c3ccccc3)cc2)cc1C

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ESR2 Q92731 1/20 0.44
MAPT P10636 3/20 0.38
ALDH1A1 P00352 3/20 0.38
L3MBTL1 Q9Y468 2/20 0.38
KDM4E B2RXH2 1/20 0.38
CYP1A2 P05177 1/20 0.38
CYP3A4 P08684 1/20 0.38
CYP2D6 P10635 1/20 0.38
CYP2C9 P11712 1/20 0.38
CYP2C19 P33261 1/20 0.38
TDP1 Q9NUW8 1/20 0.38
MEN1 O00255 1/20 0.36
APAF1 O14727 1/20 0.36
NPC1 O15118 1/20 0.36
LMNA P02545 1/20 0.36
THRB P10828 1/20 0.36
XBP1 P17861 1/20 0.36
PTBP1 P26599 1/20 0.36
HTT P42858 1/20 0.36
RAB9A P51151 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2604756 0.98 ESR2 (0.43) ESR2MAPTALDH1A1L3MBTL1KDM4E
SCHEMBL2604759 0.98 ESR2 (0.43) ESR2MAPTALDH1A1L3MBTL1KDM4E
SCHEMBL17811595 0.96 MAPT (0.42) ESR2MAPTALDH1A1L3MBTL1KDM4E
SCHEMBL13990075 0.96 L3MBTL1 (0.42) ESR2MAPTALDH1A1L3MBTL1KDM4E
SCHEMBL14179890 0.95 ESR2 (0.41) ESR2MAPTALDH1A1L3MBTL1KDM4E
SCHEMBL17199756 0.94 ESR2 (0.52) ESR2MAPTALDH1A1L3MBTL1KDM4E
SCHEMBL15870794 0.94 ESR2 (0.52) ESR2MAPTALDH1A1L3MBTL1KDM4E
SCHEMBL16684006 0.93 MCL1 (0.40) ESR2MAPTALDH1A1L3MBTL1KDM4E
SCHEMBL19595343 0.93 ESR2 (0.50) ESR2MAPTALDH1A1L3MBTL1KDM4E
SCHEMBL19651527 0.93 ESR2 (0.50) ESR2MAPTALDH1A1L3MBTL1KDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 36 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9434877-B2 Organic electroluminescent device MERCK PATENT GMBH (DE) 2016-09-06 US disclosed
US-9434877-B2 Organic electroluminescent device MERCK PATENT GMBH (DE) 2016-09-06 US disclosed
US-9356242-B2 Organic electroluminescent device MERCK PATENT GMBH (DE) 2016-05-31 US disclosed
US-9356242-B2 Organic electroluminescent device MERCK PATENT GMBH (DE) 2016-05-31 US disclosed
US-20150295184-A1 ORGANIC ELECTROLUMINESCENT DEVICE MERCK PATENT GMBH (DE) 2015-10-15 US disclosed
US-20150295184-A1 ORGANIC ELECTROLUMINESCENT DEVICE MERCK PATENT GMBH (DE) 2015-10-15 US disclosed
US-9054319-B2 Organic electroluminescence device IDEMITSU KOSAN CO., LTD. (JP) 2015-06-09 US disclosed
US-9054319-B2 Organic electroluminescence device IDEMITSU KOSAN CO., LTD. (JP) 2015-06-09 US disclosed
US-8941297-B2 Organic electroluminescent device MERCK PATENT GMBH (DE) 2015-01-27 US disclosed
US-8941297-B2 Organic electroluminescent device MERCK PATENT GMBH (DE) 2015-01-27 US disclosed
US-20120091438-A1 ORGANIC ELECTROLUMINESCENT ELEMENT IDEMITSU KOSAN CO., LTD. (JP) 2012-04-19 US disclosed
US-20120074395-A1 ORGANIC ELECTROLUMINESCENT ELEMENT IDEMITSU KOSAN CO., LTD. (JP) 2012-03-29 US disclosed
US-20120074395-A1 ORGANIC ELECTROLUMINESCENT ELEMENT IDEMITSU KOSAN CO., LTD. (JP) 2012-03-29 US disclosed
US-8106391-B2 Organic EL device IDEMITSU KOSAN CO., LTD. (JP) 2012-01-31 US disclosed
US-8106391-B2 Organic EL device IDEMITSU KOSAN CO., LTD. (JP) 2012-01-31 US disclosed
WO-2011110262-A1 ORGANIC ELECTROLUMINESCENT DEVICE MERCK PATENT GMBH (DE) 2011-09-15 WO disclosed
US-20100283043-A1 ORGANIC EL ELEMENT IDEMITSU LOSAN CO., LTD. 2010-11-11 US disclosed
US-20100283043-A1 ORGANIC EL ELEMENT IDEMITSU LOSAN CO., LTD. 2010-11-11 US disclosed
US-20100219404-A1 ORGANIC EL DEVICE IDEMITSU KOSAN CO., LTD. (JP) 2010-09-02 US disclosed
US-20100219404-A1 ORGANIC EL DEVICE IDEMITSU KOSAN CO., LTD. (JP) 2010-09-02 US disclosed