Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IGF1R | P08069 | 10/20 | 0.49 |
| ▸ | DNM2 | P50570 | 2/20 | 0.48 |
| ▸ | AURKA | O14965 | 1/20 | 0.41 |
| ▸ | PAK4 | O96013 | 1/20 | 0.41 |
| ▸ | PAK1 | Q13153 | 1/20 | 0.41 |
| ▸ | FGFR1 | P11362 | 2/20 | 0.41 |
| ▸ | KDR | P35968 | 2/20 | 0.41 |
| ▸ | PKN1 | Q16512 | 1/20 | 0.40 |
| ▸ | CCNK | O75909 | 1/20 | 0.39 |
| ▸ | CDK13 | Q14004 | 1/20 | 0.39 |
| ▸ | CDK12 | Q9NYV4 | 1/20 | 0.39 |
| ▸ | CCR4 | P51679 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25371017 | 0.78 | IGF1R (0.68) | IGF1RPAK4PAK1CCNKCDK13 | |
| SCHEMBL30558769 | 0.78 | IGF1R (0.68) | IGF1RPAK4PAK1CCNKCDK13 | |
| SCHEMBL19477221 | 0.72 | DNM2 (0.80) | DNM2CCR4 | |
| SCHEMBL19476566 | 0.72 | DNM2 (0.80) | DNM2CCR4 | |
| SCHEMBL25370935 | 0.68 | IGF1R (0.59) | IGF1RPAK4PAK1CCNKCDK13 | |
| SCHEMBL2947094 | 0.68 | DNM2 (0.90) | DNM2CCR4 | |
| SCHEMBL4017963 | 0.66 | IGF1R (1.00) | IGF1RFGFR1KDR | |
| SCHEMBL12487500 | 0.66 | DNM2 (0.53) | DNM2CCR4 | |
| SCHEMBL26047955 | 0.65 | CCNK (0.66) | IGF1RPAK4PAK1CCNKCDK13 | |
| SCHEMBL25368424 | 0.65 | IGF1R (0.54) | IGF1RPAK4PAK1CCNKCDK13 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023164611-A1 | MODULATORS OF MYC FAMILY PROTO-ONCOGENE PROTEIN | NALO THERAPEUTICS (US) | 2023-08-31 | — | — | WO | disclosed |