Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CSNK2A1 | P68400 | 20/20 | 0.74 |
| ▸ | CSNK2A2 | P19784 | 18/20 | 0.74 |
| ▸ | CSNK2B | P67870 | 15/20 | 0.74 |
| ▸ | HDAC1 | Q13547 | 4/20 | 0.57 |
| ▸ | CSNK2A3 | Q8NEV1 | 4/20 | 0.57 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26048821 | 0.92 | CSNK2A1 (0.63) | CSNK2A1CSNK2A2CSNK2BHDAC1CSNK2A3 | |
| SCHEMBL26048826 | 0.92 | CSNK2A2 (0.63) | CSNK2A1CSNK2A2CSNK2BHDAC1CSNK2A3 | |
| SCHEMBL25370461 | 0.90 | CSNK2A1 (0.71) | CSNK2A1CSNK2A2CSNK2BHDAC1CSNK2A3 | |
| SCHEMBL27320316 | 0.90 | CSNK2A1 (0.76) | CSNK2A1CSNK2A2CSNK2BHDAC1CSNK2A3 | |
| SCHEMBL25287236 | 0.87 | CSNK2A1 (0.81) | CSNK2A1CSNK2A2CSNK2BHDAC1CSNK2A3 | |
| SCHEMBL29900318 | 0.86 | CSNK2A1 (0.65) | CSNK2A1CSNK2A2CSNK2BHDAC1CSNK2A3 | |
| SCHEMBL25370767 | 0.86 | CSNK2A1 (0.65) | CSNK2A1CSNK2A2CSNK2BHDAC1CSNK2A3 | |
| SCHEMBL26049047 | 0.86 | CSNK2A1 (0.65) | CSNK2A1CSNK2A2CSNK2BHDAC1CSNK2A3 | |
| SCHEMBL10131520 | 0.85 | CSNK2A1 (1.00) | CSNK2A1CSNK2A2CSNK2BHDAC1CSNK2A3 | |
| SCHEMBL27375040 | 0.85 | CSNK2A1 (0.63) | CSNK2A1CSNK2A2CSNK2BHDAC1CSNK2A3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230250097-A1 | BENZO[C][2,6]NAPHTHYRIDINE DERIVATIVES, COMPOSITIONS AND THERAPEUTIC USES THEREOF | Apollo Therapeutics Limited (GB) | 2023-08-10 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230250097-A1 | BENZO[C][2,6]NAPHTHYRIDINE DERIVATIVES, COMPOSITIONS AND THERAPEUTIC USES THEREOF | CSNK1A1, CSNK1D, CSNK2A1 | CSNK2A1 3/4885CSNK2A2 5/4885CSNK2B 8/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.