SCHEMBL29900318

SCHEMBL29900318

CC(C)(C)OC(=O)NCCCCOCCNc1nc2cc(C(=O)O)ccc2c2cnccc12

nearest known ligand 0.65

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
CSNK2A1 P68400 18/20 0.65
CSNK2A2 P19784 17/20 0.65
CSNK2B P67870 14/20 0.65
HDAC1 Q13547 4/20 0.55
CSNK2A3 Q8NEV1 4/20 0.55
BRD4 O60885 1/20 0.55
HDAC6 Q9UBN7 1/20 0.55
LATS1 O95835 1/20 0.51

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25370767 1.00 CSNK2A1 (0.65) CSNK2A1CSNK2A2CSNK2BHDAC1CSNK2A3
SCHEMBL25371719 0.93 CSNK2A1 (0.56) CSNK2A1CSNK2A2CSNK2BHDAC1CSNK2A3
SCHEMBL26049255 0.93 CSNK2A2 (0.56) CSNK2A1CSNK2A2CSNK2BHDAC1CSNK2A3
SCHEMBL30803559 0.93 CSNK2A1 (0.55) CSNK2A1CSNK2A2CSNK2BHDAC1CSNK2A3
SCHEMBL30803489 0.92 CSNK2A1 (0.65) CSNK2A1CSNK2A2CSNK2BHDAC1CSNK2A3
SCHEMBL27320168 0.92 CSNK2A1 (0.65) CSNK2A1CSNK2A2CSNK2BHDAC1CSNK2A3
SCHEMBL27319994 0.90 CSNK2A1 (0.67) CSNK2A1CSNK2A2CSNK2BHDAC1CSNK2A3
SCHEMBL30803507 0.87 CSNK2A1 (0.59) CSNK2A1CSNK2A2CSNK2BHDAC1CSNK2A3
SCHEMBL25371343 0.86 CSNK2A2 (0.49) CSNK2A1CSNK2A2CSNK2BHDAC1CSNK2A3
SCHEMBL29900367 0.86 CSNK2A2 (0.49) CSNK2A1CSNK2A2CSNK2BHDAC1CSNK2A3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4584265-A1 NOVEL COMPOUNDS, COMPOSITIONS AND THERAPEUTIC USES THEREOF Cambridge Enterprise Limited (GB) 2025-07-16 EP disclosed
WO-2024052690-A1 NOVEL COMPOUNDS, COMPOSITIONS AND THERAPEUTIC USES THEREOF CAMBRIDGE ENTERPRISE LIMITED (GB) 2024-03-14 WO disclosed
EP-4301752-A1 BENZO[C][2,6]NAPHTHYRIDINE DERIVATIVES, COMPOSITIONS AND THERAPEUTIC USES THEREOF Cambridge Enterprise Limited (GB) 2024-01-10 EP disclosed
WO-2022185041-A1 BENZO[C][2,6]NAPHTHYRIDINE DERIVATIVES, COMPOSITIONS AND THERAPEUTIC USES THEREOF CAMBRIDGE ENTERPRISE LIMITED (GB) 2022-09-09 WO disclosed