SCHEMBL26049067

SCHEMBL26049067

Cc1c(C)c(C)c(CNCCCCOCCOc2nc3cc(C(N)=O)ccc3c3cnccc23)c(C)c1C

nearest known ligand 0.43

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
CSNK2A2 P19784 18/20 0.43
CSNK2B P67870 17/20 0.43
CSNK2A1 P68400 11/20 0.42
PIM1 P11309 1/20 0.42
PIM2 Q9P1W9 1/20 0.42
PARP1 P09874 1/20 0.39
CSNK2A3 Q8NEV1 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL26049075 0.93 CSNK2A2 (0.49) CSNK2A2CSNK2BCSNK2A1PARP1
SCHEMBL26049012 0.87 CSNK2A1 (0.56) CSNK2A2CSNK2BCSNK2A1PIM1PIM2
SCHEMBL26049044 0.86 CSNK2A2 (0.43) CSNK2A2CSNK2BCSNK2A1PIM1PIM2
SCHEMBL25369974 0.85 CSNK2A2 (0.51) CSNK2A2CSNK2BCSNK2A1PIM1PIM2
SCHEMBL29900380 0.85 CSNK2A2 (0.51) CSNK2A2CSNK2BCSNK2A1PIM1PIM2
SCHEMBL26048832 0.84 CSNK2A2 (0.53) CSNK2A2CSNK2BCSNK2A1PIM1PIM2
SCHEMBL29900158 0.84 CSNK2A2 (0.38) CSNK2A2CSNK2BCSNK2A1PIM1PIM2
SCHEMBL25372087 0.84 CSNK2A2 (0.38) CSNK2A2CSNK2BCSNK2A1PIM1PIM2
SCHEMBL25371668 0.83 CSNK2A2 (0.46) CSNK2A2CSNK2BCSNK2A1PIM1PIM2
SCHEMBL29900184 0.83 CSNK2A2 (0.46) CSNK2A2CSNK2BCSNK2A1PIM1PIM2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230250097-A1 BENZO[C][2,6]NAPHTHYRIDINE DERIVATIVES, COMPOSITIONS AND THERAPEUTIC USES THEREOF Apollo Therapeutics Limited (GB) 2023-08-10 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230250097-A1 BENZO[C][2,6]NAPHTHYRIDINE DERIVATIVES, COMPOSITIONS AND THERAPEUTIC USES THEREOF CSNK1A1, CSNK1D, CSNK2A1 CSNK2A2 5/4885CSNK2B 8/4885CSNK2A1 3/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.