SCHEMBL26049075

SCHEMBL26049075

Cc1c(C)c(C)c(CNCCCCOCCOc2nc3cc(C(=O)O)ccc3c3cnccc23)c(C)c1C

nearest known ligand 0.49

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
CSNK2A2 P19784 18/20 0.49
CSNK2B P67870 16/20 0.49
CSNK2A1 P68400 12/20 0.49
PARP1 P09874 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL26049067 0.93 CSNK2A2 (0.43) CSNK2A2CSNK2BCSNK2A1PARP1
SCHEMBL26049047 0.86 CSNK2A1 (0.65) CSNK2A2CSNK2BCSNK2A1
SCHEMBL26049073 0.86 CSNK2A2 (0.47) CSNK2A2CSNK2BCSNK2A1PARP1
SCHEMBL26048829 0.84 CSNK2A2 (0.56) CSNK2A2CSNK2BCSNK2A1PARP1
SCHEMBL25371288 0.84 CSNK2A2 (0.43) CSNK2A2CSNK2BCSNK2A1PARP1
SCHEMBL29900203 0.84 CSNK2A2 (0.43) CSNK2A2CSNK2BCSNK2A1PARP1
SCHEMBL29900197 0.83 CSNK2A2 (0.47) CSNK2A2CSNK2BCSNK2A1PARP1
SCHEMBL25368974 0.83 CSNK2A2 (0.47) CSNK2A2CSNK2BCSNK2A1PARP1
SCHEMBL29900324 0.83 CSNK2A2 (0.50) CSNK2A2CSNK2BCSNK2A1PARP1
SCHEMBL25369065 0.83 CSNK2A2 (0.50) CSNK2A2CSNK2BCSNK2A1PARP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230250097-A1 BENZO[C][2,6]NAPHTHYRIDINE DERIVATIVES, COMPOSITIONS AND THERAPEUTIC USES THEREOF Apollo Therapeutics Limited (GB) 2023-08-10 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230250097-A1 BENZO[C][2,6]NAPHTHYRIDINE DERIVATIVES, COMPOSITIONS AND THERAPEUTIC USES THEREOF CSNK1A1, CSNK1D, CSNK2A1 CSNK2A2 5/4885CSNK2B 8/4885CSNK2A1 3/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.