SCHEMBL26049255

SCHEMBL26049255

CC(C)(C)OC(=O)NCCCCOCCNc1nc2cc(C(N)=O)ccc2c2cnccc12

nearest known ligand 0.56

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
CSNK2A2 P19784 14/20 0.56
CSNK2A1 P68400 14/20 0.56
CSNK2B P67870 11/20 0.56
BRD4 O60885 4/20 0.53
LATS1 O95835 1/20 0.49
HDAC1 Q13547 4/20 0.48
CSNK2A3 Q8NEV1 4/20 0.48
HDAC6 Q9UBN7 1/20 0.48
STING1 Q86WV6 1/20 0.48
PIM1 P11309 1/20 0.47
PIM2 Q9P1W9 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29900318 0.93 CSNK2A1 (0.65) CSNK2A2CSNK2A1CSNK2BBRD4LATS1
SCHEMBL25370767 0.93 CSNK2A1 (0.65) CSNK2A2CSNK2A1CSNK2BBRD4LATS1
SCHEMBL25371719 0.92 CSNK2A1 (0.56) CSNK2A2CSNK2A1CSNK2BBRD4LATS1
SCHEMBL30803395 0.92 BRD4 (0.58) CSNK2A2CSNK2A1CSNK2BBRD4LATS1
SCHEMBL27320179 0.92 BRD4 (0.58) CSNK2A2CSNK2A1CSNK2BBRD4LATS1
SCHEMBL30803559 0.91 CSNK2A1 (0.55) CSNK2A2CSNK2A1CSNK2BBRD4LATS1
SCHEMBL30803377 0.90 LATS1 (0.60) CSNK2A2CSNK2A1CSNK2BBRD4LATS1
SCHEMBL27320008 0.90 LATS1 (0.60) CSNK2A2CSNK2A1CSNK2BBRD4LATS1
SCHEMBL26049275 0.87 STING1 (0.48) CSNK2A2CSNK2A1CSNK2BBRD4LATS1
SCHEMBL26048826 0.86 CSNK2A2 (0.63) CSNK2A2CSNK2A1CSNK2BHDAC1CSNK2A3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2024052690-A1 NOVEL COMPOUNDS, COMPOSITIONS AND THERAPEUTIC USES THEREOF CAMBRIDGE ENTERPRISE LIMITED (GB) 2024-03-14 WO disclosed
US-20230250097-A1 BENZO[C][2,6]NAPHTHYRIDINE DERIVATIVES, COMPOSITIONS AND THERAPEUTIC USES THEREOF Apollo Therapeutics Limited (GB) 2023-08-10 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230250097-A1 BENZO[C][2,6]NAPHTHYRIDINE DERIVATIVES, COMPOSITIONS AND THERAPEUTIC USES THEREOF CSNK1A1, CSNK1D, CSNK2A1 CSNK2A2 5/4885CSNK2A1 3/4885CSNK2B 8/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.