Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR2 | P34972 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1090751 | 0.74 | OPRM1 (0.33) | — | |
| SCHEMBL15677560 | 0.70 | — | — | |
| SCHEMBL10202692 | 0.67 | — | — | |
| SCHEMBL15116714 | 0.65 | OPRM1 (0.32) | — | |
| SCHEMBL19473609 | 0.65 | — | — | |
| SCHEMBL26864566 | 0.65 | — | — | |
| SCHEMBL26864563 | 0.65 | — | — | |
| SCHEMBL16156075 | 0.65 | — | — | |
| SCHEMBL15125154 | 0.65 | SMN1; SMN2 (0.31) | — | |
| SCHEMBL27131379 | 0.64 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023154344-A1 | 2-METHYL-4',5'-DIHYDROSPIRO[PIPERIDINE-4,7'-THIENO[2,3-C]PYRAN] DERIVATIVES AS INHIBITORS OF APOL1 AND METHODS OF USING SAME | VERTEX PHARMACEUTICALS INCORPORATED (US) | 2023-08-17 | — | — | WO | disclosed |