Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDK2 | Q15119 | 5/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | TDP2 | O95551 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | MCL1 | Q07820 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.34 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.34 |
| ▸ | CTRC | Q99895 | 1/20 | 0.33 |
| ▸ | MGAM | O43451 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24257780 | 1.00 | PDK2 (0.46) | PDK2CYP1A2TDP2ALDH1A1MAPK1 | |
| SCHEMBL26050362 | 0.93 | PDK2 (0.41) | PDK2CYP1A2TDP2ALDH1A1MAPK1 | |
| SCHEMBL12781938 | 0.91 | MAPK1 (0.45) | PDK2TDP2ALDH1A1MAPK1MCL1 | |
| SCHEMBL16922981 | 0.91 | MAPK1 (0.45) | PDK2TDP2ALDH1A1MAPK1MCL1 | |
| SCHEMBL5359737 | 0.89 | PDK2 (0.38) | PDK2CYP1A2TDP2ALDH1A1MCL1 | |
| SCHEMBL15678833 | 0.88 | MAPK1 (0.42) | PDK2TDP2ALDH1A1MAPK1MCL1 | |
| SCHEMBL16922978 | 0.88 | MAPK1 (0.45) | PDK2TDP2ALDH1A1MAPK1MCL1 | |
| SCHEMBL20690840 | 0.88 | PDK2 (0.41) | PDK2LMNAMAPTKMT2ASMN1; SMN2 | |
| SCHEMBL30233610 | 0.88 | PDK2 (0.41) | PDK2LMNAMAPTKMT2ASMN1; SMN2 | |
| SCHEMBL12781961 | 0.88 | ALDH1A1 (0.48) | PDK2TDP2ALDH1A1MAPK1MCL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230271989-A1 | METAL COMPLEXES | UDC IRELAND LIMITED (IE) | 2023-08-31 | — | — | US | disclosed |
| US-20230271989-A1 | METAL COMPLEXES | UDC IRELAND LIMITED (IE) | 2023-08-31 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230271989-A1 | METAL COMPLEXES | AP3M1, AP1M1, AP2M1 | PDK2 1385/4885CYP1A2 4158/4885TDP2 2702/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.