Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC6 | Q9UBN7 | 19/20 | 0.44 |
| ▸ | HDAC8 | Q9BY41 | 3/20 | 0.43 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.41 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.41 |
| ▸ | WNT1 | P04628 | 1/20 | 0.39 |
| ▸ | GSK3B | P49841 | 1/20 | 0.39 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.39 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26053755 | 0.89 | HDAC6 (0.48) | HDAC6HDAC8HDAC1HDAC3WNT1 | |
| SCHEMBL26051086 | 0.84 | HDAC6 (0.50) | HDAC6HDAC8HDAC1HDAC3 | |
| SCHEMBL10224031 | 0.84 | HDAC6 (0.47) | HDAC6HDAC8HDAC1HDAC3HDAC11 | |
| SCHEMBL30620407 | 0.83 | NNMT (0.46) | — | |
| SCHEMBL10224291 | 0.83 | HDAC6 (0.46) | HDAC6HDAC8HDAC1HDAC3 | |
| SCHEMBL26051120 | 0.83 | HDAC6 (0.41) | HDAC6HDAC8HDAC1HDAC3HDAC11 | |
| SCHEMBL10224246 | 0.82 | HDAC6 (0.43) | HDAC6HDAC8HDAC1HDAC3HDAC11 | |
| SCHEMBL722257 | 0.81 | HDAC6 (0.43) | HDAC6HDAC8HDAC1HDAC3 | |
| SCHEMBL26062657 | 0.80 | HDAC6 (0.52) | HDAC6HDAC1HDAC3 | |
| SCHEMBL26051096 | 0.80 | HDAC6 (0.49) | HDAC6HDAC8HDAC1HDAC3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023150203-A1 | HDAC6 INHIBITORS AND USES THEREOF | EIKONIZO THERAPEUTICS, INC. (US) | 2023-08-10 | — | — | WO | disclosed |