Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.42 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.42 |
| ▸ | PNMT | P11086 | 1/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | GLA | P06280 | 1/20 | 0.41 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.34 |
| ▸ | PDCD1LG2 | Q9BQ51 | 3/20 | 0.33 |
| ▸ | CD274 | Q9NZQ7 | 3/20 | 0.33 |
| ▸ | PDE2A | O00408 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23113953 | 0.84 | CYP1A2 (0.47) | LMNACYP1A2CYP3A4CYP2D6NFKB1 | |
| SCHEMBL17040428 | 0.81 | LMNA (0.38) | LMNACYP1A2CYP3A4CYP2D6NFKB1 | |
| Hydrochloric Acid SCHEMBL30484048 | 0.79 | LMNA (0.36) | LMNACYP1A2CYP3A4CYP2D6NFKB1 | |
| SCHEMBL18854482 | 0.76 | PDE2A (0.38) | LMNACYP1A2CYP3A4CYP2D6NFKB1 | |
| SCHEMBL23336900 | 0.76 | PDE2A (0.38) | LMNACYP1A2CYP3A4CYP2D6NFKB1 | |
| Hydrochloric Acid SCHEMBL23303738 | 0.74 | PDE2A (0.37) | LMNATP53HTTALDH1A1GLA | |
| Hydrochloric Acid SCHEMBL23303736 | 0.74 | PDE2A (0.37) | LMNATP53HTTALDH1A1GLA | |
| SCHEMBL26050842 | 0.74 | CYP1A2 (0.46) | LMNACYP1A2CYP3A4CYP2D6NFKB1 | |
| Hydrochloric Acid SCHEMBL17764459 | 0.72 | LMNA (0.66) | LMNACYP1A2CYP3A4CYP2D6NFKB1 | |
| SCHEMBL23114100 | 0.72 | HTT (0.41) | LMNACYP1A2CYP3A4HTTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3793994-B1 | INHIBITING AGENTS FOR BRUTON'S TYROSINE KINASE | BIOGEN MA INC (US) | 2023-08-23 | — | — | EP | disclosed |