SCHEMBL26052263

SCHEMBL26052263

c1ccc(-n2c3ccccc3c3ccc(-c4nc(-c5cccc6c5oc5ccccc56)nc(-c5cccc6c5oc5ccccc56)n4)cc32)cc1

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALOX5 P09917 2/20 0.43
KDM4E B2RXH2 3/20 0.40
ATM Q13315 2/20 0.40
L3MBTL1 Q9Y468 1/20 0.40
PRKDC P78527 5/20 0.37
PIK3CD O00329 1/20 0.36
PIK3CB P42338 1/20 0.36
ALDH1A1 P00352 3/20 0.33
GGPS1 O95749 1/20 0.33
PPARG P37231 1/20 0.33
RXFP1 Q9HBX9 1/20 0.33
NR2E3 Q9Y5X4 1/20 0.33
NCOR2 Q9Y618 1/20 0.33
MAPT P10636 2/20 0.33
SIRT2 Q8IXJ6 1/20 0.33
SIRT1 Q96EB6 1/20 0.33
TSHR P16473 3/20 0.32
LMNA P02545 2/20 0.32
HSD17B10 Q99714 2/20 0.32
MAPK1 P28482 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL26051773 0.98 ALOX5 (0.41) ALOX5KDM4EATML3MBTL1PRKDC
SCHEMBL16810881 0.98 ALOX5 (0.41) ALOX5KDM4EATML3MBTL1PRKDC
SCHEMBL16810971 0.97 ALOX5 (0.40) ALOX5KDM4EATML3MBTL1PRKDC
SCHEMBL26080499 0.96 ALOX5 (0.40) ALOX5KDM4EATML3MBTL1PRKDC
SCHEMBL16811054 0.96 ALOX5 (0.40) ALOX5KDM4EATML3MBTL1PRKDC
SCHEMBL23948002 0.95 ALOX5 (0.39) ALOX5KDM4EATML3MBTL1PRKDC
SCHEMBL25945421 0.95 ALOX5 (0.39) ALOX5KDM4EATML3MBTL1PRKDC
SCHEMBL26080569 0.95 ALOX5 (0.39) ALOX5KDM4EATML3MBTL1PRKDC
SCHEMBL23947791 0.94 ALOX5 (0.38) ALOX5KDM4EATML3MBTL1PRKDC
SCHEMBL23947355 0.94 ALOX5 (0.38) ALOX5KDM4EATML3MBTL1PRKDC

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4230626-A1 HETEROCYCLIC COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE COMPRISING SAME LT Materials Co., Ltd. (KR) 2023-08-23 EP disclosed