Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F7 | P08709 | 1/20 | 0.69 |
| ▸ | F3 | P13726 | 1/20 | 0.69 |
| ▸ | NR4A2 | P43354 | 2/20 | 0.64 |
| ▸ | PYGL | P06737 | 1/20 | 0.54 |
| ▸ | NHERF1 | O14745 | 4/20 | 0.51 |
| ▸ | GABRP | O00591 | 2/20 | 0.49 |
| ▸ | GABRD | O14764 | 2/20 | 0.49 |
| ▸ | GABRA1 | P14867 | 2/20 | 0.49 |
| ▸ | GABRB1 | P18505 | 2/20 | 0.49 |
| ▸ | GABRG2 | P18507 | 2/20 | 0.49 |
| ▸ | GABRB3 | P28472 | 2/20 | 0.49 |
| ▸ | GABRA5 | P31644 | 2/20 | 0.49 |
| ▸ | GABRA3 | P34903 | 2/20 | 0.49 |
| ▸ | GABRA2 | P47869 | 2/20 | 0.49 |
| ▸ | GABRB2 | P47870 | 2/20 | 0.49 |
| ▸ | GABRA4 | P48169 | 2/20 | 0.49 |
| ▸ | GABRE | P78334 | 2/20 | 0.49 |
| ▸ | GABRA6 | Q16445 | 2/20 | 0.49 |
| ▸ | GABRG1 | Q8N1C3 | 2/20 | 0.49 |
| ▸ | GABRG3 | Q99928 | 2/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28287772 | 0.90 | F7 (0.59) | F7F3NR4A2PYGLNHERF1 | |
| SCHEMBL3181314 | 0.88 | NR4A2 (0.64) | F7F3NR4A2PYGL | |
| SCHEMBL31368069 | 0.86 | F7 (0.71) | F7F3NR4A2PYGLNHERF1 | |
| SCHEMBL14631289 | 0.84 | F7 (0.69) | F7F3NR4A2PYGLNHERF1 | |
| SCHEMBL5912617 | 0.82 | F7 (0.75) | F7F3NR4A2PYGLNHERF1 | |
| SCHEMBL24143246 | 0.82 | F7 (0.65) | F7F3NR4A2PYGLNHERF1 | |
| SCHEMBL1434913 | 0.82 | F7 (1.00) | F7F3NR4A2PYGLNHERF1 | |
| SCHEMBL14067804 | 0.81 | KDM4E (0.57) | — | |
| SCHEMBL24144238 | 0.81 | NR4A2 (0.64) | F7F3NR4A2GABRA1GABRB1 | |
| SCHEMBL6699986 | 0.81 | NR4A2 (0.72) | F7F3NR4A2PYGLNHERF1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11731967-B2 | Inhibitors of TRIM33 and methods of use | DANA-FARBER CANCER INSTITUTE, INC. (US) | 2023-08-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11731967-B2 | Inhibitors of TRIM33 and methods of use | TRIM33, TRIM28, TRIM4 | F7 4840/4885F3 2605/4885NR4A2 1409/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.