SCHEMBL260553

SCHEMBL260553

O=C(O)c1c(F)cccc1F

nearest known ligand 0.67

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CES2 O00748 4/20 0.67
CES1 P23141 4/20 0.67
ALB P02768 1/20 0.54
CA12 O43570 2/20 0.52
CA1 P00915 2/20 0.52
CA2 P00918 2/20 0.52
CA7 P43166 2/20 0.52
CA9 Q16790 2/20 0.52
CA14 Q9ULX7 2/20 0.52
TTR P02766 1/20 0.50
TDP1 Q9NUW8 2/20 0.48
LMNA P02545 1/20 0.48
MEN1 O00255 1/20 0.47
KMT2A Q03164 1/20 0.47
BCHE P06276 1/20 0.46
NPC1 O15118 1/20 0.46
RAB9A P51151 1/20 0.46
JAK2 O60674 1/20 0.44
JAK1 P23458 1/20 0.44
TYK2 P29597 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL7968059 0.97 CES2 (0.64) CES2CES1ALBCA12CA1
SCHEMBL3117223 0.97 CES2 (0.64) CES2CES1ALBCA12CA1
Biphenyl SCHEMBL2831439 0.91 CES2 (0.56) CES2CES1ALBCA12CA1
Formic Acid SCHEMBL28286083 0.91 CES2 (0.56) CES2CES1ALBCA12CA1
SCHEMBL28138125 0.89 CES2 (0.54) CES2CES1ALBCA12CA1
SCHEMBL27763941 0.89 CES2 (0.54) CES2CES1ALBCA12CA1
Acetamide SCHEMBL4743556 0.89 CES2 (0.54) CES2CES1ALBCA12CA1
Propene SCHEMBL27785695 0.87 CES2 (0.52) CES2CES1ALBCA12CA1
SCHEMBL335939 0.85 ALB (0.63) CES2CES1ALBCA12CA1
SCHEMBL617480 0.85 CA12 (0.70) CES2CES1ALBCA12CA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1755 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4661890-A1 PTP1B/TC-PTP DUAL INHIBITORS AND PROTEIN DEGRADERS Purdue Research Foundation (US) 2025-12-17 EP claimed
US-12497636-B2 Recombinant Saccharomyces cerevisiae cells for cannabinoid production NATIONAL UNIVERSITY OF SINGAPORE (SG) 2025-12-16 US claimed
WO-2025202864-A1 ENT1 INHIBITORS IN COMBINATION WITH ONCOLYTIC VIRUSES AND THEIR USE IN THE TREATMENT OF CANCER iTeos Belgium SA (BE) 2025-10-02 WO claimed
WO-2025126110-A1 ENT1 INHIBITORS IN COMBINATION WITH BISPECIFIC ANTIBODIES iTeos Belgium SA (BE) 2025-06-19 WO claimed
WO-2025104613-A1 ENT1 INHIBITORS IN COMBINATION WITH CHECKPOINT INHIBITORS iTeos Belgium SA (BE) 2025-05-22 WO claimed
CN-119735758-A Long-acting composite tracer material for oil-gas well and preparation method thereof 北京晨础石油科技有限公司 2025-04-01 CN claimed
CN-115458724-B High-energy-density composite positive electrode material and preparation method and application thereof 中国科学院深圳先进技术研究院 2025-03-25 CN claimed
CN-119613699-A Method for removing perfluoro polyether acyl fluoride end group 南开大学 2025-03-14 CN claimed
CN-119552359-A Cation modified polyimide resin and preparation method thereof 江苏集萃功能材料研究所有限公司 2025-03-04 CN claimed
CN-119431308-A Diamine monomer, self-repairing thermoplastic polyimide resin and preparation method thereof 江苏集萃功能材料研究所有限公司 2025-02-14 CN claimed
US-20050090690-A1 Process for preparing tetra-amide compounds XEROX CORPORATION 2005-04-28 US claimed
US-20040094297-A1 Method for determining the extent of recovery of materials injected into oil wells or subsurface formations during oil and gas exploration and production CORE LABORATORIES LP 2004-05-20 US claimed
US-6659175-B2 Mixing water, buffers, oxidizers, gels, gelation inhibitors, stabilizer and curing agents with tracers, then pumping the mixtures into bores, withdrawing fluids and measuring concentration of labels; well completion efficiency CORE LABORATORIES, INC. 2003-12-09 US claimed
US-20030006036-A1 Mixing water, buffers, oxidizers, gels, gelation inhibitors, stabilizer and curing agents with tracers, then pumping the mixtures into bores, withdrawing fluids and measuring concentration of labels; well completion efficiency CORE LABORATORIES GLOBAL N.V. (NL) 2003-01-09 US claimed
WO-2002095189-A1 METHOD OF DETERMINING THE EXTENT OF RECOVERY OF MATERIALS INJECTED INTO OIL WELLS CORE LABORATORIES L.P. (US) 2002-11-28 WO claimed
US-5354495-A Homo- or copolymerizable through ethylenic unsaturation NIPPON PAINT CO., LTD. (JP) 1994-10-11 US claimed
EP-0177122-B1 ACRYLAMIDE DERIVATIVES Nippon Paint Co., Ltd. (JP) 1992-04-01 EP claimed
US-4935413-A ELASTICITY, ADHESION AND DISPERSIBILITY NIPPON PAINT CO., LTD. (JP) 1990-06-19 US claimed
EP-0228564-A2 Novel insecticidal diacylhydrazine compounds AMERICAN CYANAMID COMPANY (US) 1987-07-15 EP claimed
US-4411974-A FOR NEGATIVE TONERS XEROX CORPORATION (US) 1983-10-25 US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20050090690-A1 Process for preparing tetra-amide compounds TAF9, TAF5, TAF1 CES2 2351/4885CES1 3786/4885ALB 137/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.