Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATM | Q13315 | 2/20 | 0.54 |
| ▸ | POLB | P06746 | 1/20 | 0.54 |
| ▸ | HTR2A | P28223 | 7/20 | 0.44 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.41 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.41 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.41 |
| ▸ | HTR2B | P41595 | 4/20 | 0.40 |
| ▸ | HTR2C | P28335 | 3/20 | 0.40 |
| ▸ | HTR1A | P08908 | 1/20 | 0.39 |
| ▸ | HTR1D | P28221 | 1/20 | 0.39 |
| ▸ | HTR1B | P28222 | 1/20 | 0.39 |
| ▸ | HTR1E | P28566 | 1/20 | 0.39 |
| ▸ | HTR7 | P34969 | 1/20 | 0.39 |
| ▸ | HTR5A | P47898 | 1/20 | 0.39 |
| ▸ | HTR6 | P50406 | 1/20 | 0.39 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.38 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.38 |
| ▸ | DRD2 | P14416 | 1/20 | 0.38 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.38 |
| ▸ | DRD1 | P21728 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26056124 | 0.82 | HTR2A (0.62) | ATMHTR2AHTR2BHTR2CTAAR1 | |
| SCHEMBL26056807 | 0.82 | POLB (0.49) | ATMPOLBHTR2ACHRM2CHRM1 | |
| SCHEMBL26056129 | 0.79 | HTR2A (0.49) | HTR2ACHRM2CHRM1HTR2CADRB2 | |
| SCHEMBL4320087 | 0.75 | POLB (0.65) | ATMPOLBHTR2ACHRM2CHRM1 | |
| SCHEMBL14213768 | 0.74 | POLB (0.62) | ATMPOLBHTR2ACHRM2CHRM1 | |
| Hydrochloric Acid SCHEMBL9829288 | 0.74 | POLB (0.62) | ATMPOLBHTR2ACHRM2CHRM1 | |
| SCHEMBL26013317 | 0.74 | HTR2A (0.69) | ATMPOLBHTR2AHTR2BHTR2C | |
| SCHEMBL8635081 | 0.70 | ATM (1.00) | ATMPOLBCA12CA1CA2 | |
| SCHEMBL557799 | 0.70 | ATM (1.00) | ATMPOLBCA12CA1CA2 | |
| SCHEMBL30230461 | 0.70 | ATM (1.00) | ATMPOLBCA12CA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023156453-A1 | PHENETHYLAMINE DERIVATIVES, COMPOSITIONS, AND METHODS OF USE | CYBIN IRL LIMITED (IE) | 2023-08-24 | — | — | WO | disclosed |