Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC5A1 | P13866 | 6/20 | 0.49 |
| ▸ | SLC5A2 | P31639 | 6/20 | 0.49 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 3/20 | 0.37 |
| ▸ | KDM4A | O75164 | 1/20 | 0.37 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 4/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 2/20 | 0.33 |
| ▸ | P2RX3 | P56373 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10031323 | 0.78 | SLC5A1 (0.54) | SLC5A1SLC5A2HIF1AMAPTKDM4A | |
| SCHEMBL10064922 | 0.75 | SLC5A1 (0.57) | SLC5A1SLC5A2HIF1AMAPTKDM4A | |
| SCHEMBL26892230 | 0.74 | SLC5A2 (0.58) | SLC5A1SLC5A2HIF1AMAPTKDM4A | |
| SCHEMBL26892322 | 0.74 | SLC5A1 (0.56) | SLC5A1SLC5A2MAPTKDM4AKDM4C | |
| SCHEMBL24921357 | 0.74 | SLC5A2 (0.71) | SLC5A1SLC5A2 | |
| SCHEMBL26816497 | 0.72 | SLC5A2 (0.54) | SLC5A1SLC5A2HIF1AMAPTKDM4A | |
| SCHEMBL24952863 | 0.72 | SLC5A2 (0.54) | SLC5A1SLC5A2HIF1AMAPTKDM4A | |
| SCHEMBL16845135 | 0.72 | SLC5A1 (0.56) | SLC5A1SLC5A2HIF1AMAPTKDM4A | |
| SCHEMBL10031310 | 0.71 | SLC5A1 (0.56) | SLC5A1SLC5A2HIF1AMAPTKDM4A | |
| SCHEMBL24980512 | 0.71 | SLC5A1 (0.44) | SLC5A1SLC5A2HIF1AMAPTLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4234012-A2 | SGLT2 INHIBITORS FOR TREATMENT OF METABOLIC DISORDERS IN CANINE ANIMALS | Boehringer Ingelheim Vetmedica GmbH (DE) | 2023-08-30 | — | — | EP | disclosed |