Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC5A1 | P13866 | 6/20 | 0.54 |
| ▸ | SLC5A2 | P31639 | 6/20 | 0.54 |
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | KDM4A | O75164 | 1/20 | 0.46 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 3/20 | 0.43 |
| ▸ | POLB | P06746 | 2/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.39 |
| ▸ | P2RX3 | P56373 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4857102 | 0.83 | SLC5A1 (0.38) | SLC5A1SLC5A2MAPTLMNAALDH1A1 | |
| SCHEMBL10064922 | 0.81 | SLC5A1 (0.57) | SLC5A1SLC5A2MAPTKDM4AKDM4C | |
| SCHEMBL16845135 | 0.80 | SLC5A1 (0.56) | SLC5A1SLC5A2MAPTKDM4AKDM4C | |
| SCHEMBL10031310 | 0.80 | SLC5A1 (0.56) | SLC5A1SLC5A2MAPTKDM4AKDM4C | |
| SCHEMBL10031313 | 0.78 | SLC5A1 (0.54) | SLC5A1SLC5A2MAPTKDM4AKDM4C | |
| SCHEMBL26057442 | 0.78 | SLC5A1 (0.49) | SLC5A1SLC5A2MAPTKDM4AKDM4C | |
| SCHEMBL19114941 | 0.75 | SLC5A1 (0.51) | SLC5A1SLC5A2MAPTKDM4AKDM4C | |
| SCHEMBL10031312 | 0.74 | SLC5A1 (0.50) | SLC5A1SLC5A2MAPTKDM4AKDM4C | |
| SCHEMBL23436552 | 0.73 | SLC5A1 (0.54) | SLC5A1SLC5A2MAPTKDM4AKDM4C | |
| SCHEMBL14862842 | 0.73 | SLC5A2 (0.80) | SLC5A1SLC5A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120053330-A1 | Chemical Process | GLAXOSMITHKLINE LLC | 2012-03-01 | — | — | US | disclosed |
| US-20120053330-A1 | Chemical Process | GLAXOSMITHKLINE LLC | 2012-03-01 | — | — | US | disclosed |
| WO-2010127067-A1 | CHEMICAL PROCESS | GLAXOSMITHKLINE LLC (US) | 2010-11-04 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120053330-A1 | Chemical Process | SLC5A2, SLC5A1, UGGT1 | SLC5A1 2/4885SLC5A2 1/4885MAPT 1329/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.