Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | CA3 | P07451 | 2/20 | 0.39 |
| ▸ | CA5A | P35218 | 2/20 | 0.39 |
| ▸ | CA5B | Q9Y2D0 | 2/20 | 0.39 |
| ▸ | CA12 | O43570 | 1/20 | 0.39 |
| ▸ | CA2 | P00918 | 1/20 | 0.39 |
| ▸ | CA4 | P22748 | 1/20 | 0.39 |
| ▸ | CA6 | P23280 | 1/20 | 0.39 |
| ▸ | CA7 | P43166 | 1/20 | 0.39 |
| ▸ | CA9 | Q16790 | 1/20 | 0.39 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.37 |
| ▸ | DRD4 | P21917 | 7/20 | 0.37 |
| ▸ | DRD2 | P14416 | 6/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6446695 | 0.94 | POLB (0.46) | POLBALDH1A1SMN1; SMN2KDM4EMAPT | |
| SCHEMBL7292154 | 0.92 | MEN1 (0.45) | POLBALDH1A1SMN1; SMN2KDM4EMAPT | |
| SCHEMBL2845918 | 0.87 | POLB (0.42) | POLBALDH1A1SMN1; SMN2KDM4EMAPT | |
| SCHEMBL260275 | 0.84 | POLB (0.38) | POLBALDH1A1SMN1; SMN2CA3CA5A | |
| SCHEMBL18622113 | 0.82 | POLB (0.57) | POLBALDH1A1SMN1; SMN2KDM4EMAPT | |
| SCHEMBL9355210 | 0.82 | POLB (0.57) | POLBALDH1A1SMN1; SMN2KDM4EMAPT | |
| SCHEMBL16316312 | 0.82 | POLB (0.50) | POLBALDH1A1SMN1; SMN2KDM4EMAPT | |
| SCHEMBL26161761 | 0.82 | EPHX1 (0.48) | POLBALDH1A1SMN1; SMN2KDM4EMAPT | |
| SCHEMBL18536691 | 0.80 | POLB (0.49) | POLBALDH1A1SMN1; SMN2KDM4EMAPT | |
| SCHEMBL10633351 | 0.80 | MEN1 (0.58) | POLBALDH1A1SMN1; SMN2KDM4EMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8445612-B2 | Conjugation reactions | BIOCOMPATIBLES UK LIMITED (GB) | 2013-05-21 | — | — | US | disclosed |
| US-8445612-B2 | Conjugation reactions | BIOCOMPATIBLES UK LIMITED (GB) | 2013-05-21 | — | — | US | disclosed |
| US-20120016082-A1 | CONJUGATION REACTIONS | BIOCOMPATIBLES UK LIMITED (GB) | 2012-01-19 | — | — | US | disclosed |
| US-8053520-B2 | Conjugation reactions | BIOCOMPATIBLES UK LIMITED (GB) | 2011-11-08 | — | — | US | disclosed |
| US-20100099678-A1 | DIALKYLAMINO ALKYL ESTERS OF PIVAGABINE AS MEDICAMENTS FOR THE TREATMENT OF CENTRAL NERVOUS SYSTEM DISORDERS | CENERX BIOPHARMA (US) | 2010-04-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120016082-A1 | CONJUGATION REACTIONS | PHPT1, GNE, MGMT | POLB 284/4885ALDH1A1 1053/4885SMN1; SMN2 3385/4885 |
| US-20100099678-A1 | DIALKYLAMINO ALKYL ESTERS OF PIVAGABINE AS MEDICAMENTS FOR THE TREATMENT OF CENTRAL NERVOUS SYSTEM DISORDERS | PMP22, CNR2, COQ8A | POLB 1224/4885ALDH1A1 2193/4885SMN1; SMN2 65/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.