SCHEMBL26060413

SCHEMBL26060413

CC(C)(C)Cc1ccc2c(-c3ccccc3)ncnc2c1

nearest known ligand 0.53

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ADORA2A P29274 1/20 0.53
PIK3CA P42336 2/20 0.39
PIK3CG P48736 2/20 0.39
PIK3CD O00329 1/20 0.39
PIK3CB P42338 1/20 0.39
MTOR P42345 1/20 0.39
JAK2 O60674 1/20 0.38
EGFR P00533 9/20 0.38
KDM4E B2RXH2 2/20 0.35
HTT P42858 2/20 0.35
GRM4 Q14833 1/20 0.35
ALDH1A1 P00352 1/20 0.35
LMNA P02545 1/20 0.35
HPGD P15428 1/20 0.35
RET P07949 1/20 0.35
KDR P35968 1/20 0.35
CAMKK1 Q8N5S9 1/20 0.35
CAMKK2 Q96RR4 1/20 0.35
LCK P06239 1/20 0.35
AAK1 Q2M2I8 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20809355 0.86 ADORA2A (0.35) ADORA2APIK3CAPIK3CGPIK3CDPIK3CB
SCHEMBL20809356 0.82 KIT (0.36) ADORA2AJAK2EGFRRETKDR
SCHEMBL20809338 0.77 SCN9A (0.41) KDM4EALDH1A1HPGDMAPK1
SCHEMBL20809346 0.76 PDE10A (0.35) ADORA2AKDM4EALDH1A1HPGDKDR
SCHEMBL13584672 0.75 ADORA2A (0.62) ADORA2APIK3CAPIK3CGPIK3CDPIK3CB
SCHEMBL20809139 0.73 TRPV1 (0.33) ADORA2AEGFRKDM4EHTTALDH1A1
SCHEMBL4727551 0.72 ADORA2A (0.62) ADORA2APIK3CAPIK3CGPIK3CDPIK3CB
SCHEMBL24795853 0.72 PIK3CG (0.34) ADORA2APIK3CAPIK3CGPIK3CDPIK3CB
SCHEMBL4728722 0.71 ADORA2A (0.53) ADORA2AEGFRGRM4KDRCAMKK1
SCHEMBL20809144 0.71 SIK2 (0.34) ADORA2AJAK2EGFRRETKDR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230287263-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2023-09-14 US disclosed
US-11692132-B2 Organic electroluminescent materials and devices UNIVERSAL DISPLAY CORPORATION (US) 2023-07-04 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11692132-B2 Organic electroluminescent materials and devices OSBP, OCIAD1, OCIAD2 ADORA2A 2435/4885PIK3CA 3353/4885PIK3CG 1663/4885
US-20230287263-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES OSBP, OCIAD1, OCIAD2 ADORA2A 2435/4885PIK3CA 3353/4885PIK3CG 1663/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.