SCHEMBL20809355

SCHEMBL20809355

Cc1cc(C)cc(-c2ncnc3cc(CC(C)(C)C)ccc23)c1

nearest known ligand 0.36

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ADORA2A P29274 1/20 0.35
CAMKK1 Q8N5S9 1/20 0.33
CAMKK2 Q96RR4 1/20 0.33
KDM4E B2RXH2 2/20 0.33
HTT P42858 2/20 0.33
ALDH1A1 P00352 1/20 0.33
CHRM4 P08173 1/20 0.33
ESR1 P03372 1/20 0.32
CLK4 Q9HAZ1 1/20 0.32
SIK2 Q9H0K1 1/20 0.31
MAP4K4 O95819 1/20 0.31
MAPK1 P28482 1/20 0.31
SUV39H1 O43463 1/20 0.31
PRMT1 Q99873 1/20 0.31
TRPV1 Q8NER1 1/20 0.31
SCN9A Q15858 1/20 0.31
EGFR P00533 2/20 0.31
KIT P10721 1/20 0.31
MAPT P10636 1/20 0.31
IRAK4 Q9NWZ3 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20809356 0.88 KIT (0.36) ADORA2ACAMKK1CAMKK2CLK4SIK2
SCHEMBL20809139 0.87 TRPV1 (0.33) ADORA2ACAMKK1CAMKK2KDM4EHTT
SCHEMBL26060413 0.86 ADORA2A (0.53) ADORA2ACAMKK1CAMKK2KDM4EHTT
SCHEMBL24795853 0.85 PIK3CG (0.34) ADORA2ACAMKK1CAMKK2KDM4EHTT
SCHEMBL20809353 0.82 CAMKK1 (0.37) ADORA2ACAMKK1CAMKK2KDM4EHTT
SCHEMBL24796188 0.80 ADORA2A (0.42) ADORA2ACAMKK1CAMKK2KDM4EHTT
SCHEMBL24795164 0.78 CAMKK1 (0.38) ADORA2ACAMKK1CAMKK2
SCHEMBL24795847 0.77 CAMKK1 (0.33) CAMKK1CAMKK2KIT
SCHEMBL20809339 0.77 SCN9A (0.41) ESR1SCN9A
SCHEMBL20809347 0.77 ESR1 (0.32) ESR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10957869-B2 Organic luminescent materials containing cycloalkyl ancillary ligands Beijing Summer Sprout Technology Co., Ltd. (CN) 2021-03-23 US disclosed
US-20190103574-A1 ORGANIC LUMINESCENT MATERIALS CONTAINING CYCLOALKYL ANCILLARY LIGANDS Beijing Summer Sprout Technology Co., Ltd. (CN) 2019-04-04 US disclosed
US-20190077818-A1 ORGANIC LUMINESCENT MATERIALS CONTAINING FLUORINE ANCILLARY LIGANDS Beijing Summer Sprout Technology Co., Ltd. (CN) 2019-03-14 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20190103574-A1 ORGANIC LUMINESCENT MATERIALS CONTAINING CYCLOALKYL ANCILLARY LIGANDS ACAT1, ACACA, ACAT2 ADORA2A 187/4885CAMKK1 1632/4885CAMKK2 1382/4885
US-10957869-B2 Organic luminescent materials containing cycloalkyl ancillary ligands ACAT1, ACACA, ACAT2 ADORA2A 187/4885CAMKK1 1632/4885CAMKK2 1382/4885
US-20190077818-A1 ORGANIC LUMINESCENT MATERIALS CONTAINING FLUORINE ANCILLARY LIGANDS FOXO1, NAA15, FOXK1 ADORA2A 163/4885CAMKK1 3553/4885CAMKK2 3452/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.