Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDK2 | Q15119 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12864447 | 0.96 | PDK2 (0.34) | PDK2 | |
| SCHEMBL10053635 | 0.81 | PDK2 (0.39) | PDK2 | |
| SCHEMBL12864440 | 0.80 | ABCG2 (0.31) | — | |
| SCHEMBL12864449 | 0.78 | PDK2 (0.33) | PDK2 | |
| SCHEMBL2605980 | 0.74 | PDK2 (0.32) | PDK2 | |
| SCHEMBL12864439 | 0.73 | PDK2 (0.31) | PDK2 | |
| SCHEMBL13649833 | 0.73 | ALDH1A1 (0.37) | PDK2 | |
| SCHEMBL16631234 | 0.72 | ESR1 (0.33) | PDK2 | |
| SCHEMBL12864424 | 0.71 | PDK2 (0.35) | PDK2 | |
| SCHEMBL2605986 | 0.71 | PDK2 (0.41) | PDK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2260023-B1 | FLUORENE DERIVATIVES FOR ORGANIC ELECTROLUMINESCENCE DEVICES | MERCK PATENT GMBH (DE) | 2012-04-25 | — | — | EP | disclosed |