Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR2 | P34972 | 9/20 | 0.36 |
| ▸ | CNR1 | P21554 | 6/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 3/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.36 |
| ▸ | SMYD3 | Q9H7B4 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.33 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.33 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.33 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.33 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.33 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.33 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.33 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26303631 | 1.00 | CNR2 (0.36) | CNR2CNR1SMN1; SMN2MEN1KMT2A | |
| SCHEMBL25029992 | 0.94 | DRD2 (0.33) | CNR2CNR1SMN1; SMN2KMT2ASMYD3 | |
| SCHEMBL25029513 | 0.94 | DRD2 (0.33) | CNR2CNR1SMN1; SMN2KMT2ASMYD3 | |
| SCHEMBL25030380 | 0.94 | DRD2 (0.33) | CNR2CNR1SMN1; SMN2KMT2ASMYD3 | |
| SCHEMBL26204538 | 0.89 | CNR2 (0.37) | CNR2CNR1SMN1; SMN2MEN1KMT2A | |
| SCHEMBL26303635 | 0.89 | CNR2 (0.37) | CNR2CNR1SMN1; SMN2MEN1KMT2A | |
| SCHEMBL25029512 | 0.89 | CNR2 (0.37) | CNR2CNR1SMN1; SMN2MEN1KMT2A | |
| SCHEMBL25029514 | 0.88 | CNR2 (0.36) | CNR2CNR1SMN1; SMN2MEN1KMT2A | |
| SCHEMBL25029996 | 0.86 | MAPT (0.30) | MAPT | |
| SCHEMBL26058591 | 0.86 | MAPT (0.30) | MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023161874-A1 | CYTOTOXICITY TARGETING CHIMERAS FOR C-C CHEMOKINE RECEPTOR 2-EXPRESSING CELLS | GLAXOSMITHKLINE INTELLECTUAL PROPERTY DEVELOPMENT LIMITED (GB) | 2023-08-31 | — | — | WO | disclosed |