Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NAMPT | P43490 | 7/20 | 0.40 |
| ▸ | THRB | P10828 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 5/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.37 |
| ▸ | TP53 | P04637 | 3/20 | 0.37 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | MLYCD | O95822 | 2/20 | 0.36 |
| ▸ | RAB9A | P51151 | 2/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | MAOA | P21397 | 1/20 | 0.34 |
| ▸ | CNR1 | P21554 | 1/20 | 0.34 |
| ▸ | DRD4 | P21917 | 1/20 | 0.34 |
| ▸ | ACHE | P22303 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10060550 | 0.82 | MEN1 (0.48) | THRBTSHRHPGDALDH1A1TP53 | |
| SCHEMBL16693316 | 0.80 | THRB (0.45) | THRBTSHRHPGDALDH1A1TP53 | |
| SCHEMBL5579284 | 0.79 | EGFR (0.40) | THRBTSHRHPGDALDH1A1TP53 | |
| SCHEMBL18058938 | 0.78 | EGFR (0.36) | NAMPTTHRBTSHRHPGDALDH1A1 | |
| SCHEMBL13512783 | 0.78 | TSHR (0.50) | TSHRHPGDALDH1A1CYP3A4HSD17B10 | |
| SCHEMBL24788139 | 0.76 | THRB (0.46) | THRBTSHRHPGDALDH1A1TP53 | |
| SCHEMBL12370889 | 0.73 | THRB (0.55) | THRBTSHRHPGDALDH1A1CYP3A4 | |
| SCHEMBL20925178 | 0.73 | THRB (0.45) | THRBTSHRHPGDALDH1A1TP53 | |
| SCHEMBL21115682 | 0.72 | THRB (0.43) | THRBTSHRHPGDALDH1A1TP53 | |
| SCHEMBL13512762 | 0.72 | TSHR (0.54) | THRBTSHRHPGDALDH1A1CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2444429-A1 | Led curable compositions | Agfa-Gevaert (BE) | 2012-04-25 | — | — | EP | disclosed |