Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A | P28223 | 1/20 | 0.38 |
| ▸ | HTR2C | P28335 | 1/20 | 0.38 |
| ▸ | HTR2B | P41595 | 1/20 | 0.38 |
| ▸ | NOS2 | P35228 | 1/20 | 0.33 |
| ▸ | HSD17B3 | P37058 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 3/20 | 0.31 |
| ▸ | ALDH1A2 | O94788 | 2/20 | 0.31 |
| ▸ | ALDH2 | P05091 | 2/20 | 0.31 |
| ▸ | ALDH1B1 | P30837 | 2/20 | 0.31 |
| ▸ | ALDH1A3 | P47895 | 2/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24163664 | 0.84 | HTR2A (0.41) | HTR2AHTR2CHTR2BHSD17B10 | |
| SCHEMBL24163655 | 0.81 | HTR2A (0.41) | HTR2AHTR2CHTR2BNOS2ALDH1A1 | |
| SCHEMBL29991772 | 0.80 | HTR2A (0.59) | HTR2AHTR2CHTR2BALDH1A1KDM4E | |
| SCHEMBL19073223 | 0.79 | KDM4E (0.36) | HTR2AHTR2CHTR2BALDH1A1KDM4E | |
| SCHEMBL26065403 | 0.74 | SLC5A2 (0.30) | HTR2AHTR2CHTR2B | |
| SCHEMBL15447924 | 0.71 | KDM4E (0.33) | HTR2AHTR2CHTR2BALDH1A1KDM4E | |
| SCHEMBL24163647 | 0.70 | HTR2A (0.41) | HTR2AHTR2CHTR2B | |
| SCHEMBL26065401 | 0.70 | KCNA3 (0.39) | ALDH1A1KDM4EHPGDHSD17B10CYP1A1 | |
| SCHEMBL26065399 | 0.70 | TLR8 (0.33) | HTR2AHTR2CHSD17B3ALDH1A1KDM4E | |
| SCHEMBL19073140 | 0.69 | HTR2A (0.31) | HTR2AHTR2CHTR2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230265045-A1 | PHENALKYLAMINES AND METHODS OF TREATING MOOD DISORDERS | GILGAMESH PHARMACEUTICALS, INC. (US) | 2023-08-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230265045-A1 | PHENALKYLAMINES AND METHODS OF TREATING MOOD DISORDERS | PNMT, HTR2C, HTR2A | HTR2A 3/4885HTR2C 2/4885HTR2B 6/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.