Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.44 |
| ▸ | HPGD | P15428 | 2/20 | 0.44 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.42 |
| ▸ | CNR2 | P34972 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.41 |
| ▸ | TRPV4 | Q9HBA0 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
| ▸ | ATM | Q13315 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25372869 | 0.87 | TRPV4 (0.42) | ALDH1A1KDM4EHSD17B10HPGDADRB2 | |
| SCHEMBL25372864 | 0.87 | TRPV4 (0.42) | ALDH1A1KDM4EHSD17B10HPGDADRB2 | |
| SCHEMBL26066191 | 0.87 | USP2 (0.41) | ALDH1A1KDM4EHSD17B10HPGDADRB2 | |
| SCHEMBL26065774 | 0.84 | TLR7 (0.42) | ALDH1A1KDM4EMAPK1CNR2TRPV4 | |
| SCHEMBL26065889 | 0.84 | EBP (0.44) | CNR2TRPV4 | |
| SCHEMBL26065891 | 0.82 | TRPV4 (0.41) | ALDH1A1KDM4EHPGDMAPK1TRPV4 | |
| SCHEMBL26065762 | 0.82 | EBP (0.39) | ALDH1A1KDM4EHSD17B10HPGDMAPK1 | |
| SCHEMBL26065920 | 0.82 | EBP (0.39) | ALDH1A1KDM4EHSD17B10HPGDMAPK1 | |
| SCHEMBL26065919 | 0.82 | EBP (0.39) | ALDH1A1KDM4EHSD17B10HPGDMAPK1 | |
| SCHEMBL26065776 | 0.81 | TRPV4 (0.38) | ALDH1A1KDM4EADRB2MAPK1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023164063-A1 | EMOPAMIL-BINDING PROTEIN INHIBITORS AND USES THEREOF | BIOGEN MA INC. (US) | 2023-08-31 | — | — | WO | disclosed |