Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNH2 | Q12809 | 2/20 | 0.43 |
| ▸ | EBP | Q15125 | 4/20 | 0.40 |
| ▸ | CA2 | P00918 | 1/20 | 0.40 |
| ▸ | PSEN1 | P49768 | 1/20 | 0.38 |
| ▸ | PSEN2 | P49810 | 1/20 | 0.38 |
| ▸ | APH1B | Q8WW43 | 1/20 | 0.38 |
| ▸ | NCSTN | Q92542 | 1/20 | 0.38 |
| ▸ | APH1A | Q96BI3 | 1/20 | 0.38 |
| ▸ | PSENEN | Q9NZ42 | 1/20 | 0.38 |
| ▸ | CNR2 | P34972 | 3/20 | 0.38 |
| ▸ | TPSAB1 | Q15661 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26066147 | 0.92 | KCNH2 (0.42) | KCNH2CA2TPSAB1 | |
| SCHEMBL25371219 | 0.87 | PSEN1 (0.37) | KCNH2EBPCA2PSEN1PSEN2 | |
| SCHEMBL26065889 | 0.87 | EBP (0.44) | KCNH2EBPPSEN1PSEN2APH1B | |
| SCHEMBL26066093 | 0.84 | MEN1 (0.41) | — | |
| SCHEMBL26065533 | 0.82 | EBP (0.41) | KCNH2EBPCA2CNR2TPSAB1 | |
| SCHEMBL26065762 | 0.81 | EBP (0.39) | KCNH2EBPCNR2TPSAB1 | |
| SCHEMBL26065920 | 0.81 | EBP (0.39) | KCNH2EBPCNR2TPSAB1 | |
| SCHEMBL26065919 | 0.81 | EBP (0.39) | KCNH2EBPCNR2TPSAB1 | |
| SCHEMBL26066246 | 0.81 | PSEN1 (0.51) | KCNH2EBPPSEN1PSEN2APH1B | |
| SCHEMBL26065523 | 0.79 | EBP (0.41) | KCNH2EBPCNR2TPSAB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023164063-A1 | EMOPAMIL-BINDING PROTEIN INHIBITORS AND USES THEREOF | BIOGEN MA INC. (US) | 2023-08-31 | — | — | WO | disclosed |